SCHEMBL135863

SCHEMBL135863

C#CCCCCCCCCCCCCO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.50
MAPT P10636 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
USP2 O75604 3/20 0.46
CYP3A4 P08684 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
ALDH1A1 P00352 5/20 0.39
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TSHR P16473 1/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
MIF P14174 1/20 0.35
ALOX15 P16050 1/20 0.34
GPR84 Q9NQS5 1/20 0.33
FFAR1 O14842 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2335615 1.00 HSD17B10 (0.50) HSD17B10MAPTCYP1A2CYP2D6CYP2C9
SCHEMBL8966804 1.00 HSD17B10 (0.50) HSD17B10MAPTCYP1A2CYP2D6CYP2C9
SCHEMBL18975256 1.00 HSD17B10 (0.50) HSD17B10MAPTCYP1A2CYP2D6CYP2C9
SCHEMBL23014949 1.00 HSD17B10 (0.50) HSD17B10MAPTCYP1A2CYP2D6CYP2C9
SCHEMBL128978 1.00 HSD17B10 (0.50) HSD17B10MAPTCYP1A2CYP2D6CYP2C9
SCHEMBL23014965 1.00 HSD17B10 (0.50) HSD17B10MAPTCYP1A2CYP2D6CYP2C9
SCHEMBL130671 1.00
SCHEMBL130493 1.00 HSD17B10 (0.50) HSD17B10MAPTCYP1A2CYP2D6CYP2C9
SCHEMBL8907249 1.00 HSD17B10 (0.50) HSD17B10MAPTCYP1A2CYP2D6CYP2C9
SCHEMBL131692 1.00 HSD17B10 (0.50) HSD17B10MAPTCYP1A2CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111943821-B Synthesis method of (13 cis, 15 trans) -octadecadienal 苏州华道生物药业股份有限公司 2022-04-05 CN claimed
CN-111943821-A Synthesis method of (13 cis, 15 trans) -octadecadienal 苏州华道生物药业股份有限公司 2020-11-17 CN claimed
WO-2014001527-A2 LIPID ANALYSIS Rheinische Friedrich-Wilhelms-Universität Bonn (DE) 2014-01-03 WO claimed
US-20260103438-A1 PROBES AND METHODS TO IDENTIFY LIGANDABLE FATTY ACYLATION SITES FOR THERAPEUTIC TARGET IDENTIFICATION MASSACHUSETTS GEN HOSPITAL (US) 2026-04-16 US disclosed
WO-2024073486-A9 PROBES AND METHODS TO IDENTIFY LIGANDABLE FATTY ACYLATION SITES FOR THERAPEUTIC TARGET IDENTIFICATION THE GENERAL HOSPITAL CORPORATION (US) 2024-11-21 WO disclosed
US-20240360163-A1 Nucleoside Prodrugs and Uses Related Thereto UNIV EMORY (US) 2024-10-31 US disclosed
US-12049474-B2 Nucleoside prodrugs and uses related thereto EMORY UNIVERSITY (US) 2024-07-30 US disclosed
WO-2024073486-A2 PROBES AND METHODS TO IDENTIFY LIGANDABLE FATTY ACYLATION SITES FOR THERAPEUTIC TARGET IDENTIFICATION THE GENERAL HOSPITAL CORPORATION (US) 2024-04-04 WO disclosed
US-20220298185-A1 Nucleoside Prodrugs and Uses Related Thereto UNIV EMORY (US) 2022-09-22 US disclosed
EP-4017499-A1 NUCLEOSIDE PRODRUGS AND USES RELATED THERETO Emory University (US) 2022-06-29 EP disclosed
CN-114502172-A Nucleoside prodrugs and related uses thereof 爱默蕾大学 2022-05-13 CN disclosed
EP-1535609-A1 NF-KB ACTIVATION INHIBITORS Institute of Medicinal Molecular Design, Inc. (JP) 2005-06-01 EP disclosed
EP-1514544-A1 ANTIALLERGIC Institute of Medicinal Molecular Design, Inc. (JP) 2005-03-16 EP disclosed
EP-1512396-A1 INHIBITORS AGAINST THE ACTIVATION OF AP-1 AND NFAT Institute of Medicinal Molecular Design, Inc. (JP) 2005-03-09 EP disclosed
EP-1512397-A1 O-SUBSTITUTED HYDROXYARYL DERIVATIVES Institute of Medicinal Molecular Design, Inc. (JP) 2005-03-09 EP disclosed
EP-1510210-A1 IMMUNITY-RELATED PROTEIN KINASE INHIBITORS Institute of Medicinal Molecular Design, Inc. (JP) 2005-03-02 EP disclosed
EP-1510207-A1 THERAPEUTIC DRUG FOR DIABETES Institute of Medicinal Molecular Design, Inc. (JP) 2005-03-02 EP disclosed
US-20040259877-A1 Inhibitors against the production and release of inflammatory cytokines INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2004-12-23 US disclosed
EP-1352650-A1 INHIBITORS AGAINST THE PRODUCTION AND RELEASE OF INFLAMMATORY CYTOKINES Institute of Medicinal Molecular Design, Inc. (JP) 2003-10-15 EP disclosed
US-4440940-A HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS AMERICAN CYANAMID COMPANY (US) 1984-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220298185-A1 Nucleoside Prodrugs and Uses Related Thereto PNPO, GSTO1, CYP2C18 HSD17B10 322/4885MAPT 4429/4885CYP1A2 38/4885
US-20240360163-A1 Nucleoside Prodrugs and Uses Related Thereto PNPO, GSTO1, CYP2C18 HSD17B10 322/4885MAPT 4429/4885CYP1A2 38/4885
US-12049474-B2 Nucleoside prodrugs and uses related thereto PNPO, GSTO1, CYP2C18 HSD17B10 322/4885MAPT 4429/4885CYP1A2 38/4885
US-20040259877-A1 Inhibitors against the production and release of inflammatory cytokines NFKBIA, IL1B, IKBKB HSD17B10 704/4885MAPT 2435/4885CYP1A2 1483/4885
US-20260103438-A1 PROBES AND METHODS TO IDENTIFY LIGANDABLE FATTY ACYLATION SITES FOR THERAPEUTIC TARGET IDENTIFICATION ZDHHC2, SPTLC2, SPTLC1 HSD17B10 74/4885MAPT 2842/4885CYP1A2 2581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.