Dimethylamine

Dimethylamine

SCHEMBL8907301

CCCNc1ccccc1.CNC

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.58
ALDH1A1 P00352 1/20 0.58
L3MBTL1 Q9Y468 2/20 0.50
KMT2A Q03164 1/20 0.47
TSHR P16473 1/20 0.46
KCNH3 Q9ULD8 1/20 0.42
GAA P10253 1/20 0.42
ALOX12 P18054 1/20 0.42
IDO1 P14902 1/20 0.41
TLR7 Q9NYK1 1/20 0.41
CYP1A2 P05177 2/20 0.41
APP P05067 1/20 0.41
TRPA1 O75762 1/20 0.41
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
HTT P42858 1/20 0.40
MERTK Q12866 1/20 0.40
HDAC3 O15379 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL52481 0.95 MAPT (0.64) MAPTALDH1A1L3MBTL1KMT2ATSHR
Bromide SCHEMBL5311934 0.93 MAPT (0.61) MAPTALDH1A1L3MBTL1KMT2ATSHR
Hydrochloric Acid SCHEMBL8974053 0.93 MAPT (0.61) MAPTALDH1A1L3MBTL1KMT2ATSHR
SCHEMBL28276750 0.93 MAPT (0.61) MAPTALDH1A1L3MBTL1KMT2ATSHR
Propane SCHEMBL11766700 0.93 MAPT (0.61) MAPTALDH1A1L3MBTL1KMT2ATSHR
Ammonia Solution, Strong SCHEMBL1072936 0.93 MAPT (0.61) MAPTALDH1A1L3MBTL1KMT2ATSHR
Iodide SCHEMBL32671616 0.93 MAPT (0.61) MAPTALDH1A1L3MBTL1KMT2ATSHR
SCHEMBL5950258 0.88 MAPT (0.56) MAPTALDH1A1L3MBTL1KMT2AKCNH3
Ethylamine SCHEMBL11826172 0.88 MAPT (0.56) MAPTALDH1A1L3MBTL1KMT2ATSHR
SCHEMBL809568 0.86 ALDH1A1 (0.56) MAPTALDH1A1L3MBTL1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5672605-A ADMINISTERING TO TREAT AUTOIMMUNE DISORDERS, TRANSPLANT REJECTION ABBOTT LABORATORIES (US) 1997-09-30 US disclosed
US-5583139-A Marcolide immunomodulators ABBOTT LABORATORIES (US) 1996-12-10 US disclosed
US-5527907-A IMMUNOSUPPRESSANTS ABBOTT LABORATORIES (US) 1996-06-18 US disclosed