SCHEMBL809568

SCHEMBL809568

CCCNc1ccc(Nc2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.56
ALOX12 P18054 5/20 0.56
HSD17B10 Q99714 4/20 0.56
L3MBTL1 Q9Y468 4/20 0.56
ALOX15 P16050 3/20 0.56
TSHR P16473 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
MAPK1 P28482 2/20 0.56
PTGS1 P23219 1/20 0.56
SLC6A2 P23975 1/20 0.56
PTGS2 P35354 1/20 0.56
HTR2B P41595 1/20 0.56
MAPT P10636 7/20 0.56
GAA P10253 2/20 0.56
HDAC3 O15379 1/20 0.53
HDAC1 Q13547 1/20 0.53
HDAC2 Q92769 1/20 0.53
HDAC8 Q9BY41 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
HPGD P15428 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL52481 0.91 MAPT (0.64) ALDH1A1ALOX12L3MBTL1TSHRMAPT
Hydrochloric Acid SCHEMBL8974053 0.89 MAPT (0.61) ALDH1A1ALOX12L3MBTL1TSHRMAPT
Iodide SCHEMBL32671616 0.89 MAPT (0.61) ALDH1A1ALOX12L3MBTL1TSHRMAPT
Ammonia Solution, Strong SCHEMBL1072936 0.89 MAPT (0.61) ALDH1A1ALOX12L3MBTL1TSHRMAPT
Bromide SCHEMBL5311934 0.89 MAPT (0.61) ALDH1A1ALOX12L3MBTL1TSHRMAPT
SCHEMBL28276750 0.89 MAPT (0.61) ALDH1A1ALOX12L3MBTL1TSHRMAPT
Propane SCHEMBL11766700 0.89 MAPT (0.61) ALDH1A1ALOX12L3MBTL1TSHRMAPT
SCHEMBL1849170 0.88 ALDH1A1 (0.61) ALDH1A1ALOX12HSD17B10L3MBTL1ALOX15
Dimethylamine SCHEMBL8907301 0.86 MAPT (0.58) ALDH1A1ALOX12L3MBTL1TSHRMAPT
SCHEMBL19018136 0.86 ALDH1A1 (0.68) ALDH1A1ALOX12HSD17B10L3MBTL1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1976821-B1 DIRECT ALKYLATION OF N-ALKYL-N'-PHENYL-P-PHENYLENEDIAMINE CHEMTURA CORP (US) 2011-05-25 EP claimed
EP-1976821-A1 DIRECT ALKYLATION OF N-ALKYL-N'-PHENYL-P-PHENYLENEDIAMINE CHEMTURA CORPORATION (US) 2008-10-08 EP claimed
US-7361788-B2 Direct alkylation of N-alkyl-N′-phenyl-p-phenylenediamine CHEMTURA CORPORATION (US) 2008-04-22 US claimed
WO-2007087195-A1 DIRECT ALKYLATION OF N-ALKYL-N'-PHENYL-P-PHENYLENEDIAMINE CHEMTURA CORPORATION (US) 2007-08-02 WO claimed
US-20070173668-A1 Direct alkylation of N-alkyl-N'-phenyl-p-phenylenediamine LANXESS SOLUTIONS US INC. 2007-07-26 US claimed
EP-1056711-B1 PROCESS FOR STABILISING (METHA)ACRYLIC ESTERS AGAINST UNWANTED RADICAL POLYMERISATION BASF AG (DE) 2004-10-06 EP claimed
EP-4596662-B1 AMINE CONTAINING POLYMERS AND LUBRICANT COMPOSITIONS INCLUDING SUCH POLYMERS AND METHODS OF USING THEREOF INFINEUM INT LTD (GB) 2026-04-29 EP disclosed
US-20260078315-A1 LUBRICATING OIL COMPOSITIONS FOR HYBRID ENGINES AND METHODS OF USE AND TESTING THEREOF INFINEUM INTERNATIONAL LIMITED 2026-03-19 US disclosed
US-20260062640-A1 LUBRICATING OIL COMPOSITIONS FOR IMPROVED CLEANLINESS IN AMMONIA ENGINES AND METHODS OF USE THEREOF INFINEUM INT LTD (US) 2026-03-05 US disclosed
US-20250361459-A1 LUBRICATING OIL COMPOSITIONS WITH IMPROVED WEAR PERFORMANCE AND SOOT DISPERSANCY INFINEUM INTERNATIONAL LIMITED (GB) 2025-11-27 US disclosed
US-20250320424-A1 LUBRICATING OIL COMPOSITIONS FOR HYDROGEN FUELED ENGINES FOR REDUCED PRE-IGNITION INFINEUM INTERNATIONAL LIMITED (GB) 2025-10-16 US disclosed
WO-2025215052-A1 FORMULATING WITH FUNCTIONAL POLYMERS FOR IMPROVED RETAINED FUEL ECONOMY PERFORMANCE INFINEUM INTERNATIONAL LIMITED (GB) 2025-10-16 WO disclosed
US-20250320425-A1 FORMULATING WITH FUNCTIONAL POLYMERS FOR IMPROVED RETAINED FUEL ECONOMY PERFORMANCE INFINEUM INTERNATIONAL LIMITED (GB) 2025-10-16 US disclosed
US-4797504-A HYDROXYLAMINES AND PHENYLENEDIAMINE DERIVATIVES BETZ LABORATORIES, INC. (US) 1989-01-10 US disclosed
EP-0266906-A2 Method and composition for inhibiting acrylate ester polymerization BETZ EUROPE, INC. (US) 1988-05-11 EP disclosed
EP-0252992-A1 Rubber-like polymers for tire treads, a process for their preparation, and compositions containing said polymers Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1988-01-20 EP disclosed
US-4720566-A Method and composition for inhibiting acrylonitrile polymerization BETZ LABORATORIES, INC. (US) 1988-01-19 US disclosed
US-4051067-A Stabilization of unsaturated carboxylic acid esters with mixtures of polyalkyleneamines and arylenediamines MONSANTO COMPANY (US) 1977-09-27 US disclosed
US-4016198-A Stabilization of unsaturated carboxylic acid esters with mixtures of polyalkylene-amines and arylenediamines MONSANTO COMPANY (US) 1977-04-05 US disclosed
US-3985661-A LUBRICANT-ABSORBING POWDER CARRIER SUMITOMO ELECTRIC INDUSTRIES, LTD. (JA) 1976-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070173668-A1 Direct alkylation of N-alkyl-N'-phenyl-p-phenylenediamine PNMT, AAAS, PNN ALDH1A1 663/4885ALOX12 11/4885HSD17B10 2077/4885
US-20260062640-A1 LUBRICATING OIL COMPOSITIONS FOR IMPROVED CLEANLINESS IN AMMONIA ENGINES AND METHODS OF USE THEREOF ZAP70, TBK1, IPMK ALDH1A1 3578/4885ALOX12 360/4885HSD17B10 971/4885
US-20260078315-A1 LUBRICATING OIL COMPOSITIONS FOR HYBRID ENGINES AND METHODS OF USE AND TESTING THEREOF TBK1, TMEM63A, IPMK ALDH1A1 3933/4885ALOX12 377/4885HSD17B10 2073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.