SCHEMBL8907321

SCHEMBL8907321

CC1(C)C2CCC1(CS(=O)(=O)ON1C(=O)C=CC1=O)C(=O)C2

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.56
ALDH1A1 P00352 2/20 0.53
MEN1 O00255 3/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
F2 P00734 2/20 0.52
PRSS1 P07477 2/20 0.52
PRSS2 P07478 2/20 0.52
PRSS3 P35030 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C19 P33261 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.51
KDM4E B2RXH2 1/20 0.50
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA5A P35218 2/20 0.48
CA5B Q9Y2D0 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3076355 0.87 KMT2A (0.56) KMT2AALDH1A1MEN1SMN1; SMN2F2
SCHEMBL135682 0.87 KMT2A (0.56) KMT2AALDH1A1MEN1SMN1; SMN2F2
SCHEMBL3830397 0.87 KMT2A (0.56) KMT2AALDH1A1MEN1SMN1; SMN2F2
SCHEMBL111905 0.86 KMT2A (0.55) KMT2AALDH1A1MEN1SMN1; SMN2F2
SCHEMBL5552230 0.86 KMT2A (0.55) KMT2AALDH1A1MEN1SMN1; SMN2F2
SCHEMBL452144 0.84 KMT2A (0.56) KMT2AALDH1A1MEN1SMN1; SMN2CYP1A2
SCHEMBL3823149 0.84 KMT2A (0.51) KMT2AALDH1A1MEN1SMN1; SMN2F2
SCHEMBL16519683 0.83 ALDH1A1 (0.55) KMT2AALDH1A1MEN1SMN1; SMN2F2
SCHEMBL13462915 0.83 KMT2A (0.52) KMT2AALDH1A1MEN1SMN1; SMN2F2
SCHEMBL13061579 0.83 KMT2A (0.52) KMT2AALDH1A1MEN1SMN1; SMN2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9227634-A None JP disclosed
JP-H09227634-A PHOTOACID GENERATING N-CAMPHORSULFONYLOXY-SUBSTITUTED MALEIMIDE COPOLYMER AND ITS PRODUCTION KOREA ADVANCED INST OF SCI TECHNOL 1997-09-02 JP disclosed