SCHEMBL8907377

SCHEMBL8907377

CCN1c2ccccc2Sc2cc(OC)ccc21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.60
KDM4E B2RXH2 1/20 0.60
TP53 P04637 1/20 0.60
LMNA P02545 3/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2D6 P10635 2/20 0.53
CYP3A4 P08684 2/20 0.53
KDM1A O60341 1/20 0.53
CHRM2 P08172 1/20 0.53
HTR1A P08908 1/20 0.53
ADRA2A P08913 1/20 0.53
CHRM1 P11229 1/20 0.53
DRD1 P21728 1/20 0.53
TBXA2R P21731 1/20 0.53
PTGS1 P23219 1/20 0.53
ADRA1A P35348 1/20 0.53
OPRM1 P35372 1/20 0.53
DRD3 P35462 1/20 0.53
KCNH2 Q12809 1/20 0.53
SMPD1 P17405 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19897109 0.92 SNCA (0.55) MAPK1KDM4ETP53LMNACYP1A2
SCHEMBL25258222 0.91 LMNA (0.63) MAPK1KDM4ETP53LMNACYP1A2
SCHEMBL29061585 0.89 KDM4E (0.49) MAPK1KDM4ETP53LMNACYP1A2
SCHEMBL28243422 0.83 MAPK1 (0.47) MAPK1KDM4ETP53LMNAKDM1A
SCHEMBL7123151 0.83 SNCA (0.69) MAPK1KDM4ETP53LMNAKDM1A
SCHEMBL293951 0.82 KDM1A (0.61) MAPK1KDM4ETP53LMNACYP1A2
SCHEMBL29557425 0.82 KDM1A (0.61) MAPK1KDM4ETP53LMNACYP1A2
SCHEMBL628451 0.80 KDM1A (0.49) MAPK1KDM4ETP53LMNACYP1A2
SCHEMBL29067128 0.79 KDM1A (0.67) MAPK1KDM4ETP53LMNACYP1A2
SCHEMBL7393334 0.79 MAPK1 (0.54) MAPK1KDM4ETP53LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0787230-A1 BLEACHING PROCESS COMPRISING USE OF A PHENOL OXIDIZING ENZYME, A HYDROGEN PEROXIDE SOURCE AND AN ENHANCING AGENT NOVO NORDISK A/S (DK) 1997-08-06 EP disclosed
WO-1996012846-A1 BLEACHING PROCESS COMPRISING USE OF A PHENOL OXIDIZING ENZYME, A HYDROGEN PEROXIDE SOURCE AND AN ENHANCING AGENT NOVO NORDISK A/S (DK) 1996-05-02 WO disclosed