SCHEMBL8907390

SCHEMBL8907390

CC1CCC(NC(=O)Cc2c(F)cccc2Cl)(C(=O)O)CC1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
MAPT P10636 2/20 0.49
SMN1; SMN2 Q16637 3/20 0.48
KMT2A Q03164 3/20 0.47
GAA P10253 1/20 0.47
TRPV1 Q8NER1 1/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
LMNA P02545 1/20 0.44
POLB P06746 2/20 0.44
P2RX7 Q99572 1/20 0.44
TSHR P16473 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8905949 0.92 KMT2A (0.52) ALDH1A1MAPTSMN1; SMN2KMT2AGAA
SCHEMBL8906830 0.89 ALDH1A1 (0.48) ALDH1A1MAPTSMN1; SMN2KMT2AGAA
SCHEMBL8905502 0.89 SMN1; SMN2 (0.52) ALDH1A1MAPTSMN1; SMN2KMT2AGAA
SCHEMBL8906391 0.89 ALDH1A1 (0.51) ALDH1A1MAPTSMN1; SMN2KMT2AGAA
SCHEMBL8907162 0.88 ALDH1A1 (0.50) ALDH1A1MAPTSMN1; SMN2KMT2AGAA
SCHEMBL8905521 0.88 ALDH1A1 (0.50) ALDH1A1MAPTSMN1; SMN2KMT2AGAA
SCHEMBL8906367 0.88 ALDH1A1 (0.50) ALDH1A1MAPTSMN1; SMN2KMT2AGAA
SCHEMBL8905909 0.87 ALDH1A1 (0.49) ALDH1A1MAPTSMN1; SMN2KMT2AGAA
SCHEMBL6475343 0.84 KMT2A (0.42) ALDH1A1MAPTSMN1; SMN2KMT2AGAA
SCHEMBL6771746 0.84 ALDH1A1 (0.61) ALDH1A1MAPTSMN1; SMN2KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5677449-A PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-10-14 US disclosed
US-5462913-A Pesticides, insecticides, miticides, herbicides BAYER AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed