Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2130826 | 0.87 | LMNA (0.45) | SMN1; SMN2ALDH1A1HSD17B10CYP1A2NPC1 | |
| SCHEMBL16672742 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL10744323 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22897592 | 0.75 | TDP1 (0.42) | SMN1; SMN2ALDH1A1HSD17B10TDP1NPC1 | |
| SCHEMBL30639005 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL1954072 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL28137289 | 0.74 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1HSD17B10CYP1A2NPC1 | |
| SCHEMBL14797820 | 0.74 | PSEN1 (0.41) | SMN1; SMN2ALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL16672995 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL1744701 | 0.73 | CA12 (0.47) | SMN1; SMN2TDP1KDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691278-A | HERBICIDES | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1997-11-25 | — | — | US | disclosed |