Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908032 | 1.00 | KLK7 (0.47) | KLK7GAATHRBSMN1; SMN2PARP1 | |
| SCHEMBL35211172 | 0.90 | KLK7 (0.42) | KLK7GAATHRBSMN1; SMN2PARP1 | |
| SCHEMBL4376617 | 0.83 | KLK7 (0.42) | KLK7GAATHRBSMN1; SMN2STS | |
| SCHEMBL4376621 | 0.83 | KLK7 (0.42) | KLK7GAATHRBSMN1; SMN2STS | |
| SCHEMBL6052767 | 0.83 | KLK7 (0.42) | KLK7GAATHRBSMN1; SMN2STS | |
| SCHEMBL7297892 | 0.83 | KLK7 (0.47) | KLK7PARP1STSHCRTR2GPR119 | |
| SCHEMBL12299746 | 0.82 | ABCB1 (0.46) | KLK7SMN1; SMN2KLK5L3MBTL1MEN1 | |
| SCHEMBL7301938 | 0.82 | KLK7 (0.47) | KLK7PARP1STSHCRTR2GPR119 | |
| SCHEMBL31228495 | 0.81 | KLK7 (0.46) | KLK7SMN1; SMN2PARP1STSHCRTR2 | |
| SCHEMBL31228493 | 0.81 | KLK7 (0.46) | KLK7SMN1; SMN2PARP1STSHCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |