Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.55 |
| ▸ | RXRA | P19793 | 6/20 | 0.49 |
| ▸ | RXRB | P28702 | 3/20 | 0.49 |
| ▸ | RXRG | P48443 | 3/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.47 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907781 | 0.89 | MAOB (0.53) | PPARGRXRARXRBRXRGCYP26A1 | |
| SCHEMBL6147923 | 0.83 | RXRA (0.67) | PPARGRXRARXRBRXRGCYP26A1 | |
| SCHEMBL8839066 | 0.81 | RXRA (0.52) | PPARGRXRARXRBRXRGCYP26A1 | |
| SCHEMBL9305947 | 0.80 | CA12 (0.51) | MAOBMAOA | |
| SCHEMBL8067260 | 0.80 | MAOB (0.58) | MAOBMAOA | |
| SCHEMBL5184246 | 0.79 | CYP26A1 (0.74) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL8654378 | 0.79 | XDH (0.49) | MAOBMAOA | |
| SCHEMBL7104144 | 0.79 | NPC1 (0.53) | CYP3A4MAOBMAOA | |
| SCHEMBL9272893 | 0.79 | MAOB (0.49) | PPARGRXRARXRBRXRGCYP26A1 | |
| SCHEMBL5084224 | 0.77 | CYP26A1 (0.72) | PPARGRXRARXRBRXRGCYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514264-B1 | Biaromatic compounds derived from compounds having a salicylic configuration, their preparation process and their use in human and veterinary medicine and in cosmetics | CIRD GALDERMA (FR) | 1995-11-15 | — | — | EP | claimed |
| US-5654331-A | SKIN AND RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1997-08-05 | — | — | US | disclosed |
| US-5476860-A | Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD GALDERMA) (FR) | 1995-12-19 | — | — | US | disclosed |