Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909054 | 0.95 | NCF1 (0.46) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| SCHEMBL7486790 | 0.95 | NCF1 (0.48) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| Water SCHEMBL8907275 | 0.93 | NCF1 (0.44) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| SCHEMBL8907233 | 0.91 | LOXL2 (0.44) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| SCHEMBL8907416 | 0.88 | NCF1 (0.46) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| SCHEMBL8907421 | 0.87 | NCF1 (0.52) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| SCHEMBL6495087 | 0.85 | NCF1 (0.40) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| SCHEMBL17875280 | 0.84 | KDM4E (0.47) | NCF1LOXL2MAPTKDM4EALDH1A1 | |
| SCHEMBL6482038 | 0.82 | MAPT (0.43) | NCF1LOXL2MAPTNPC1TP53 | |
| SCHEMBL6530020 | 0.82 | NCF1 (0.38) | NCF1LOXL2HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048705-A1 | POTASSIUM CHANNEL BLOCKERS | UNIVERSITY COLLEGE LONDON (GB) | 1997-12-24 | — | — | WO | disclosed |