Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.72 |
| ▸ | HTR1A | P08908 | 2/20 | 0.71 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.71 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.71 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907221 | 0.95 | HDAC6 (0.67) | HDAC6HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8907236 | 0.95 | HDAC6 (0.67) | HDAC6HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL3051350 | 0.95 | HTR1A (0.69) | HDAC6HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL31197362 | 0.95 | HTR1A (0.69) | HDAC6HTR1AADRA1DADRA1AADRA1B | |
| Water SCHEMBL8907278 | 0.94 | HDAC6 (0.65) | HDAC6HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL15761574 | 0.92 | HDAC6 (0.64) | HDAC6HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL13496054 | 0.92 | HDAC6 (0.64) | HDAC6HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL15673549 | 0.92 | HDAC6 (0.64) | HDAC6HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL30307429 | 0.92 | PKM (0.70) | HDAC6HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL15923532 | 0.92 | HTR1A (0.65) | HDAC6HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048705-A1 | POTASSIUM CHANNEL BLOCKERS | UNIVERSITY COLLEGE LONDON (GB) | 1997-12-24 | — | — | WO | disclosed |