SCHEMBL8907481

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8802769	0.86	CHRM2 (0.35)	CHRM2CHRM1CHRM3CYP4F2CYP4A11
	SCHEMBL4227993	0.81	TYR (0.41)	CHRM2CHRM1CHRM3DAOCYSLTR2
	SCHEMBL31634534	0.81	TYR (0.41)	CHRM2CHRM1CHRM3DAOCYSLTR2
	SCHEMBL19258592	0.76	MEN1 (0.43)	CHRM2CHRM1CHRM3TAAR1MEN1
	SCHEMBL27283230	0.75	TP53 (0.39)	TAAR1MEN1KMT2A
	SCHEMBL8907529	0.75	CYP4A11 (0.48)	CHRM2CHRM1CHRM3CYP4F2CYP4A11
	SCHEMBL8145669	0.75	HDAC4 (0.36)	DAOCYSLTR2CYSLTR1
	SCHEMBL19248515	0.75	CHRM2 (0.39)	CHRM2CHRM1CHRM3CYP4F2CYP4A11
	SCHEMBL6600052	0.75	ERN1 (0.43)	CHRM2CHRM1CHRM3CYP4F2CYP4A11
	SCHEMBL417948	0.75	TAAR1 (0.61)	CHRM2CHRM1CHRM3TAAR1GPR52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.