SCHEMBL8907495

SCHEMBL8907495

COc1cc(Cl)c(C=O)cc1OC.COc1ccc(C=O)c(Cl)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.64
TRIM24 O15164 1/20 0.53
TYR P14679 1/20 0.53
TRIM33 Q9UPN9 1/20 0.53
TDP1 Q9NUW8 2/20 0.52
KDM4E B2RXH2 1/20 0.52
TSHR P16473 1/20 0.52
CYP1A2 P05177 5/20 0.51
CYP1A1 P04798 4/20 0.51
CYP1B1 Q16678 4/20 0.51
ERN1 O75460 4/20 0.49
PRKDC P78527 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1236491 0.89 ALDH1A1 (0.66) ALDH1A1TRIM24TYRTRIM33TDP1
SCHEMBL1049563 0.88 ALDH1A1 (0.66) ALDH1A1TDP1KDM4ETSHRCYP1A2
SCHEMBL2199528 0.80 ERN1 (0.61) ALDH1A1TRIM24TYRTRIM33TDP1
SCHEMBL25333931 0.80 ALDH1A1 (0.58) ALDH1A1TRIM24TYRTRIM33TDP1
SCHEMBL25333119 0.79 ALDH1A1 (0.53) ALDH1A1TRIM24TYRTRIM33TDP1
SCHEMBL19563665 0.78 ALDH1A1 (0.57) ALDH1A1TRIM24TYRTRIM33TDP1
SCHEMBL8188243 0.78 ALDH1A1 (0.57) ALDH1A1TDP1KDM4ETSHRCYP1A2
SCHEMBL96291 0.78 ALDH1A1 (1.00) ALDH1A1TRIM24TYRTRIM33TDP1
SCHEMBL15054285 0.78 ALDH1A1 (0.55) ALDH1A1TDP1KDM4ETSHRCYP1A2
SCHEMBL20886497 0.77 ALDH1A1 (0.53) ALDH1A1TRIM24TYRTRIM33TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997020837-A1 PROCESS FOR THE PREPARATION OF BENZOTHIOPHENE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1997-06-12 WO disclosed