Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | PRKDC | P78527 | 2/20 | 0.59 |
| ▸ | ERN1 | O75460 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15054285 | 0.89 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL8188243 | 0.89 | ALDH1A1 (0.57) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL1787396 | 0.88 | ALDH1A1 (0.67) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL8907495 | 0.88 | ALDH1A1 (0.64) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL19628273 | 0.86 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL4065455 | 0.86 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL10394357 | 0.85 | ALDH1A1 (0.69) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL23214848 | 0.84 | PRKDC (0.61) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL1054210 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL16295565 | 0.84 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRTDP1PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257536-A2 | CYCLIC DIARYL ETHER AS ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | Amira Pharmaceuticals, Inc. (US) | 2010-12-08 | — | — | EP | claimed |
| WO-2009102893-A2 | CYCLIC DIARYL ETHER COMPOUNDS AS ANTAGONISTS OF PROSTAGLANDIN D2 receptors | AMIRA PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | WO | claimed |
| US-12173018-B2 | Penicillin-binding protein inhibitors | VenatoRx Pharmaceuticals, Inc. (US) | 2024-12-24 | — | — | US | disclosed |
| CN-111393277-B | 4-butyl polyhydroxy benzophenone compound derivative and application thereof | 山西医科大学 | 2023-01-03 | — | — | CN | disclosed |
| US-20210198288-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | VenatoRx Pharmaceuticals, Inc. | 2021-07-01 | — | — | US | disclosed |
| EP-3802551-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | Venatorx Pharmaceuticals, Inc. (US) | 2021-04-14 | — | — | EP | disclosed |
| CN-112469725-A | Penicillin binding protein inhibitors | 维纳拓尔斯制药公司 | 2021-03-09 | — | — | CN | disclosed |
| CN-111393277-A | 4-butyl polyhydroxy benzophenone compound derivative and application thereof | 山西医科大学 | 2020-07-10 | — | — | CN | disclosed |
| US-10287226-B2 | Mild catalytic reduction of C—O bonds and C═O bonds using a recyclable catalyst system | ORGANOFUEL SWEDEN AB (SE) | 2019-05-14 | — | — | US | disclosed |
| US-20170334819-A1 | A MILD CATALYTIC REDUCTION OF C-O BONDS AND C=O BONDS USING A RECYCLABLE CATALYST SYSTEM | ORGANOFUEL SWEDEN AB (SE) | 2017-11-23 | — | — | US | disclosed |
| WO-2016066835-A1 | A MILD CATALYTIC REDUCTION OF C-O BONDS AND C=O BONDS USING A RECYCLABLE CATALYST SYSTEM | CÓRDOVA ARMANDO (SE) | 2016-05-06 | — | — | WO | disclosed |
| CN-101076333-A | Pyrazolo-heteroaryl compounds useful to treat TNF-alpha and IL-1 mediated diseases | NOVARTIS AG (CH) | 2007-11-21 | — | — | CN | disclosed |
| EP-1833477-A1 | PYRAZOLO-HETEROARYL COMPOUNDS USEFUL TO TREAT TNF-ALPHA AND IL-1 MEDIATED DISEASES | Novartis AG (CH) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006100036-A1 | 3, 4-SUBSTITUTED PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF HYPERTENSION | NOVARTIS AG (CH) | 2006-09-28 | — | — | WO | disclosed |
| WO-2006063820-A1 | PYRAZOLO-HETEROARYL COMPOUNDS USEFUL TO TREAT TNF-ALPHA AND IL-1 MEDIATED DISEASES | NOVARTIS AG (CH) | 2006-06-22 | — | — | WO | disclosed |
| US-20050256159-A1 | 1,4-disubstituted piperidine derivatives and their use as 11,betahsd1 inhibitors | ASTRAZENECA AB (SE) | 2005-11-17 | — | — | US | disclosed |
| EP-1556349-A1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS 11-BETAHSD1 INHIBITORS | Astrazeneca AB (SE) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004033427-A1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS 11-BETAHSD1 INHIBITORS | ASTRAZENECA AB (SE) | 2004-04-22 | — | — | WO | disclosed |
| CN-1035828-A | Benzo benzodioxole derivatives and preparation method thereof | TANABE SEIYAKU CO (JP) | 1989-09-27 | — | — | CN | disclosed |
| US-3976695-A | Halogen substituted α-(aminoalkyl)-3,4-dihydroxybenzyl alcohols | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334819-A1 | A MILD CATALYTIC REDUCTION OF C-O BONDS AND C=O BONDS USING A RECYCLABLE CATALYST SYSTEM | CBR1, ADH1C, AOC2 | ALDH1A1 198/4885KDM4E 664/4885TSHR 4190/4885 |
| US-20210198288-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | PEPD, BPGM, EBPL | ALDH1A1 2794/4885KDM4E 2087/4885TSHR 4262/4885 |
| US-12173018-B2 | Penicillin-binding protein inhibitors | PEPD, BPGM, EBPL | ALDH1A1 2794/4885KDM4E 2087/4885TSHR 4262/4885 |
| US-10287226-B2 | Mild catalytic reduction of C—O bonds and C═O bonds using a recyclable catalyst system | CBR1, ADH1C, CBR3 | ALDH1A1 230/4885KDM4E 765/4885TSHR 4092/4885 |
| US-20050256159-A1 | 1,4-disubstituted piperidine derivatives and their use as 11,betahsd1 inhibitors | HSD11B1, HSD3B1, P4HA1 | ALDH1A1 14/4885KDM4E 1277/4885TSHR 3288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.