Propionic Acid

Propionic Acid

SCHEMBL8907700

CC(CCN)Oc1ccc(Oc2ccc(F)cc2)cc1.CCC(=O)O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
NPSR1 Q6W5P4 1/20 0.41
MEN1 O00255 1/20 0.40
MITF O75030 1/20 0.40
KMT2A Q03164 1/20 0.40
LTA4H P09960 2/20 0.40
PPARG P37231 2/20 0.39
PPARA Q07869 2/20 0.39
FNTA P49354 1/20 0.38
FNTB P49356 1/20 0.38
SLC6A9 P48067 3/20 0.37
CYP2D6 P10635 1/20 0.37
MAPT P10636 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
SLC6A5 Q9Y345 1/20 0.37
FPR2 P25090 1/20 0.37
SCN9A Q15858 1/20 0.37
ESR1 P03372 1/20 0.36
CYP19A1 P11511 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21514001 0.84 ALDH1A1 (0.45) ALDH1A1NPSR1MEN1KMT2APPARG
SCHEMBL7171301 0.76 ALDH1A1 (0.45) ALDH1A1NPSR1LTA4HPPARGPPARA
SCHEMBL2108300 0.75 ALDH1A1 (0.50) ALDH1A1NPSR1KMT2APPARGPPARA
SCHEMBL2108302 0.75 ALDH1A1 (0.50) ALDH1A1NPSR1KMT2APPARGPPARA
SCHEMBL4654975 0.74 TBXA2R (0.47) ALDH1A1NPSR1LTA4HPPARGPPARA
SCHEMBL5684816 0.74 ALDH1A1 (0.41) ALDH1A1NPSR1LTA4HMAPT
SCHEMBL10878962 0.73 NPSR1 (0.53) ALDH1A1NPSR1MEN1KMT2ALTA4H
SCHEMBL10878284 0.73 ALDH1A1 (0.44) ALDH1A1NPSR1PPARGPPARAFPR2
SCHEMBL11752042 0.71 ALDH1A1 (0.44) ALDH1A1NPSR1LTA4HPPARGPPARA
SCHEMBL11154253 0.71 CYP1A2 (0.59) ALDH1A1NPSR1KMT2APPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5700816-A ANTIARTHRITIC AGENTS G.D. SEARLE & CO. 1997-12-23 US claimed