SCHEMBL4654975

SCHEMBL4654975

CC(CCCCC(=O)O)Oc1ccc(F)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TBXA2R P21731 3/20 0.47
ALDH1A1 P00352 3/20 0.44
LTA4H P09960 2/20 0.43
PPARG P37231 2/20 0.42
PPARA Q07869 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
FFAR1 O14842 1/20 0.40
SLC6A9 P48067 3/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
SLC6A5 Q9Y345 1/20 0.40
GPR88 Q9GZN0 1/20 0.39
LMNA P02545 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7171301 0.95 ALDH1A1 (0.45) TBXA2RALDH1A1LTA4HPPARGPPARA
SCHEMBL7170118 0.81 PDE4B (0.55) ALDH1A1PPARGPPARANPSR1FFAR1
SCHEMBL11750858 0.81 LTA4H (0.45) LTA4HPPARGPPARAFFAR1
SCHEMBL4367753 0.81 MTNR1A (0.53) ALDH1A1FFAR1CYP2D6MAPTCYP2C9
SCHEMBL7175175 0.80 PPARG (0.48) ALDH1A1PPARGPPARAFFAR1
SCHEMBL7174245 0.79 PPARG (0.48) PPARGPPARAFFAR1FFAR4
SCHEMBL2108300 0.79 ALDH1A1 (0.50) ALDH1A1PPARGPPARANPSR1FFAR1
SCHEMBL2108302 0.79 ALDH1A1 (0.50) ALDH1A1PPARGPPARANPSR1FFAR1
SCHEMBL8919565 0.78 S1PR1 (0.55) ALDH1A1PPARAFFAR1MAPTFFAR4
SCHEMBL10693512 0.76 PPARD (0.52) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1113033-B1 Polyhydroxyalkanoate CANON KK (JP) 2008-11-26 EP disclosed
US-7169598-B2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2007-01-30 US disclosed
US-20040067576-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2004-04-08 US disclosed
US-6649381-B1 Biosynthesis of high purity polylactones CANON KABUSHIKI KAISHA (JP) 2003-11-18 US disclosed
US-20030208029-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2003-11-06 US disclosed
US-6586562-B2 Polylactone with units such as of 3-hydroxy-5-(4-fluorophenyl)valeric acid; biosynthesis of the polylactone by microorganism; Pseudomonas cichorii; P. putida; P. jessenii CANON KABUSHIKI KAISHA (JP) 2003-07-01 US disclosed
US-20020022253-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2002-02-21 US disclosed
EP-1113033-A2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2001-07-04 EP disclosed