Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.52 |
| ▸ | RXRA | P19793 | 9/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | HNF4A | P41235 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908240 | 0.89 | CYP26A1 (0.48) | CYP26A1CYP3A4CYP26B1RXRARARB | |
| SCHEMBL5084224 | 0.85 | CYP26A1 (0.72) | CYP26A1CYP3A4CYP26B1RXRARARB | |
| SCHEMBL8908720 | 0.79 | CYP3A4 (0.54) | CYP26A1CYP3A4CYP26B1RXRARARB | |
| SCHEMBL8907847 | 0.78 | CYP26A1 (0.55) | CYP26A1CYP3A4CYP26B1RXRARARB | |
| SCHEMBL9262524 | 0.78 | RXRA (0.48) | CYP26A1CYP3A4CYP26B1RXRARARB | |
| SCHEMBL8908927 | 0.77 | CYP3A4 (0.55) | CYP26A1CYP3A4CYP26B1RXRARARB | |
| SCHEMBL8907781 | 0.76 | MAOB (0.53) | CYP26A1CYP3A4CYP26B1RXRARARB | |
| SCHEMBL8908988 | 0.76 | CYP3A4 (0.64) | CYP26A1CYP3A4CYP26B1RXRARARB | |
| SCHEMBL5078196 | 0.75 | CYP26A1 (0.53) | CYP26A1CYP3A4CYP26B1RXRARARB | |
| SCHEMBL5084222 | 0.75 | CYP3A4 (0.63) | CYP26A1CYP3A4CYP26B1RXRARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514264-B1 | Biaromatic compounds derived from compounds having a salicylic configuration, their preparation process and their use in human and veterinary medicine and in cosmetics | CIRD GALDERMA (FR) | 1995-11-15 | — | — | EP | claimed |
| US-5654331-A | SKIN AND RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1997-08-05 | — | — | US | disclosed |
| US-5476860-A | Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD GALDERMA) (FR) | 1995-12-19 | — | — | US | disclosed |