Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.54 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.54 |
| ▸ | RXRA | P19793 | 4/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HNF4A | P41235 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907763 | 0.90 | RXRA (0.53) | CYP3A4CYP26A1CYP26B1RXRARARB | |
| SCHEMBL5184246 | 0.87 | CYP26A1 (0.74) | CYP3A4CYP26A1CYP26B1RXRARARB | |
| SCHEMBL8907597 | 0.85 | MAOB (0.49) | CYP3A4CYP26A1CYP26B1RXRARARB | |
| SCHEMBL9262524 | 0.81 | RXRA (0.48) | CYP3A4CYP26A1CYP26B1RXRARARB | |
| SCHEMBL8907781 | 0.80 | MAOB (0.53) | CYP3A4CYP26A1CYP26B1RXRARARB | |
| SCHEMBL8907733 | 0.79 | CYP26A1 (0.52) | CYP3A4CYP26A1CYP26B1RXRARARB | |
| SCHEMBL5081220 | 0.78 | CYP26A1 (0.76) | CYP3A4CYP26A1CYP26B1RXRARARB | |
| SCHEMBL5081216 | 0.78 | CYP26A1 (0.76) | CYP3A4CYP26A1CYP26B1RXRARARB | |
| SCHEMBL14157146 | 0.78 | RAB9A (0.71) | CYP3A4MAPTKMT2ARAB9ANPC1 | |
| SCHEMBL9193675 | 0.78 | CYP3A4 (0.55) | CYP3A4CYP26A1CYP26B1RXRARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654331-A | SKIN AND RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1997-08-05 | — | — | US | disclosed |