Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 5/20 | 0.33 |
| ▸ | CA1 | P00915 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | CA9 | Q16790 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055168 | 0.75 | LMNA (0.43) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL8741557 | 0.70 | LMNA (0.43) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL28818918 | 0.68 | KMT2A (0.48) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL6349798 | 0.68 | LMNA (0.39) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL367605 | 0.68 | LMNA (0.62) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL10400098 | 0.67 | KMT2A (0.45) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL13065837 | 0.67 | KMT2A (0.61) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL296106 | 0.67 | LMNA (0.48) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL27795012 | 0.66 | KMT2A (0.44) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL9762548 | 0.65 | KMT2A (0.43) | LMNATHRBCYP2C19KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775117-A1 | FLUORINATED 2-NITROIMIDAZOLE ANALOGS FOR DETECTING HYPOXIC TUMOR CELLS | SRI INTERNATIONAL (US) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996004249-A9 | FLUORINATED 2-NITROIMIDAZOLE ANALOGS FOR DETECTING HYPOXIC TUMOR CELLS | — | 1996-03-21 | — | — | WO | disclosed |
| WO-1996004249-A1 | FLUORINATED 2-NITROIMIDAZOLE ANALOGS FOR DETECTING HYPOXIC TUMOR CELLS | SRI INTERNATIONAL (US) | 1996-02-15 | — | — | WO | disclosed |