Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899789 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1CYP2C9TAS2R14 | |
| SCHEMBL23387620 | 0.87 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1CYP2C9TAS2R14 | |
| SCHEMBL20501797 | 0.87 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1CYP2C9TAS2R14 | |
| SCHEMBL23387619 | 0.87 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1CYP2C9TAS2R14 | |
| SCHEMBL7032005 | 0.87 | CYP2D6 (0.45) | ALDH1A1KMT2AMEN1CYP2C9ENPP3 | |
| SCHEMBL26655196 | 0.87 | CYP2D6 (0.45) | ALDH1A1KMT2AMEN1CYP2C9ENPP3 | |
| SCHEMBL7166740 | 0.87 | CYP2D6 (0.45) | ALDH1A1KMT2AMEN1CYP2C9ENPP3 | |
| SCHEMBL26655167 | 0.87 | CYP2D6 (0.45) | ALDH1A1KMT2AMEN1CYP2C9ENPP3 | |
| SCHEMBL21987511 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1CYP2C9TAS2R14 | |
| SCHEMBL8258339 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1CYP2C9TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |