Sugi Predict

Sugi Predict / Compounds / SCHEMBL7032005

SCHEMBL7032005

SCHEMBL7032005

Cc1ccc(S(=O)(=O)OCC2CC2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2D6 P10635 4/20 0.45
▸ CYP1A2 P05177 1/20 0.45
▸ GAA P10253 1/20 0.43
▸ ALDH1A1 P00352 6/20 0.43
▸ CYP2C9 P11712 3/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ STAT3 P40763 1/20 0.42
▸ CYP3A4 P08684 4/20 0.41
▸ CYP2C19 P33261 2/20 0.41
▸ TSHR P16473 3/20 0.41
▸ ACHE P22303 1/20 0.41
▸ CA12 O43570 1/20 0.41
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ CA3 P07451 1/20 0.41
▸ CA6 P23280 1/20 0.41
▸ CA5A P35218 1/20 0.41
▸ CA7 P43166 1/20 0.41
▸ CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26655167 1.00 CYP2D6 (0.45) CYP2D6CYP1A2GAAALDH1A1CYP2C9
SCHEMBL7166740 1.00 CYP2D6 (0.45) CYP2D6CYP1A2GAAALDH1A1CYP2C9
SCHEMBL26655196 1.00 CYP2D6 (0.45) CYP2D6CYP1A2GAAALDH1A1CYP2C9
SCHEMBL18322206 0.93 CYP2D6 (0.41) CYP2D6CYP1A2GAAALDH1A1CYP2C9
SCHEMBL10146863 0.93 CYP2D6 (0.41) CYP2D6CYP1A2GAAALDH1A1CYP2C9
SCHEMBL1482461 0.93 CYP2D6 (0.41) CYP2D6CYP1A2GAAALDH1A1CYP2C9
SCHEMBL4569135 0.93 CYP2D6 (0.41) CYP2D6CYP1A2GAAALDH1A1CYP2C9
SCHEMBL79261 0.93 ALDH1A1 (0.46) CYP2D6CYP1A2GAAALDH1A1STAT3
SCHEMBL15727900 0.93 CYP2D6 (0.43) CYP2D6CYP1A2GAAALDH1A1CYP2C9
SCHEMBL283868 0.93 ACHE (0.46) CYP2D6CYP1A2GAAALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240300899-A1 A QUINOLONE COMPOUND IN SOLID FORMS AND PROCESSES FOR THE PREPARATION THEREOF ZYDUS LIFESCIENCES LIMITED (IN) 2024-09-12 — — US disclosed
EP-4308089-A1 A QUINOLONE COMPOUND IN SOLID FORMS AND PROCESSES FOR THE PREPARATION THEREOF Zydus Lifesciences Limited (IN) 2024-01-24 — — EP disclosed
CN-116997331-A Quinolone compound in solid form and process for preparing same 兹杜斯生命科学有限公司 2023-11-03 — — CN disclosed
EP-4223751-A1 BENZAMIDE COMPOUND AND USE THEREOF Humanwell Healthcare (Group) Co., Ltd. (CN) 2023-08-09 — — EP disclosed
US-20230227445-A1 BENZAMIDE COMPOUND AND USE THEREOF HUMANWELL HEALTHCARE (GROUP) CO., LTD. (CN) 2023-07-20 — — US disclosed
US-20230227445-A1 BENZAMIDE COMPOUND AND USE THEREOF HUMANWELL HEALTHCARE (GROUP) CO., LTD. (CN) 2023-07-20 — — US disclosed
WO-2022195525-A1 A QUINOLONE COMPOUND IN SOLID FORMS AND PROCESSES FOR THE PREPARATION THEREOF ZYDUS LIFESCIENCES LIMITED (IN) 2022-09-22 — — WO disclosed
US-20120329732-A1 BENZYLBENZENE DERIVATIVES AND METHODS OF USE THERACOS, INC. (US) 2012-12-27 — — US disclosed
US-8106021-B2 Benzylbenzene derivatives and methods of use THERACOS, INC. (US) 2012-01-31 — — US disclosed
US-20110207661-A1 BENZYLBENZENE DERIVATIVES AND METHODS OF USE THERACOS, INC. (US) 2011-08-25 — — US disclosed
EP-1165562-A1 CYCLIC SUBSTITUTED FUSED PYRROLOCARBAZOLES AND ISOINDOLONES Cephalon, Inc. (US) 2002-01-02 — — EP disclosed
US-20010031745-A1 Antiviral purine derivatives UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2001-10-18 — — US disclosed
WO-2000047583-A9 CYCLIC SUBSTITUTED FUSED PYRROLOCARBAZOLES AND ISOINDOLONES CEPHALON INC (US) 2001-09-20 — — WO disclosed
WO-2000047583-A1 CYCLIC SUBSTITUTED FUSED PYRROLOCARBAZOLES AND ISOINDOLONES CEPHALON, INC. (US) 2000-08-17 — — WO disclosed
EP-0502690-B1 Cyclopropane derivative AJINOMOTO KK (JP) 1999-12-01 — — EP disclosed
US-5449840-A Viricides AJINOMOTO CO., INC. (JP) 1995-09-12 — — US disclosed
EP-0502690-A2 Cyclopropane derivative Ajinomoto Co., Inc. (JP) 1992-09-09 — — EP disclosed
US-5006570-A Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics LABORATOIRES DELAGRANGE (FR) 1991-04-09 — — US disclosed
US-4808620-A ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETIC, ANTIALLERGENS, ANTIARTHRITIC, ANTIRHEUMATIC AGENTS YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1989-02-28 — — US disclosed
EP-0254241-A1 Pyrazolopyridine compounds, their preparation and use Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1988-01-27 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110207661-A1 BENZYLBENZENE DERIVATIVES AND METHODS OF USE SLC5A2, SLC5A1, SLC2A4 CYP2D6 341/4885CYP1A2 585/4885GAA 304/4885
US-20230227445-A1 BENZAMIDE COMPOUND AND USE THEREOF P2RX3, P2RX4, P2RX7 CYP2D6 421/4885CYP1A2 571/4885GAA 1794/4885
US-20120329732-A1 BENZYLBENZENE DERIVATIVES AND METHODS OF USE SLC5A2, SLC5A1, SLC2A4 CYP2D6 341/4885CYP1A2 585/4885GAA 304/4885
US-20240300899-A1 A QUINOLONE COMPOUND IN SOLID FORMS AND PROCESSES FOR THE PREPARATION THEREOF NQO2, SQLE, RECQL CYP2D6 26/4885CYP1A2 20/4885GAA 551/4885
US-20010031745-A1 Antiviral purine derivatives PNP, TYMP, MTAP CYP2D6 1659/4885CYP1A2 3072/4885GAA 727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.