Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 14/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922323 | 0.81 | ALOX5AP (0.58) | ALOX5APCYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL8900821 | 0.79 | ALOX5AP (0.44) | ALOX5APCYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL6582909 | 0.72 | CYSLTR1 (0.61) | ALOX5APCYSLTR1CYSLTR2 | |
| SCHEMBL9081199 | 0.70 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2 | |
| SCHEMBL8891571 | 0.70 | CYSLTR1 (0.57) | ALOX5APCYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL10689480 | 0.69 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2 | |
| SCHEMBL9363352 | 0.69 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2 | |
| SCHEMBL1004347 | 0.69 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2 | |
| SCHEMBL9843295 | 0.69 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2 | |
| SCHEMBL10662425 | 0.69 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997029090-A1 | BIS-(HETEROARYLMETHOXYPHENYL)CYCLOALKYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF LEUKOTRIENE BIOSYTHESIS | ABBOTT LABORATORIES (US) | 1997-08-14 | — | — | WO | disclosed |