Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 7/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.56 |
| ▸ | CYP26B1 | Q9NR63 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 6/20 | 0.39 |
| ▸ | RXRB | P28702 | 4/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | RARG | P13631 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | HNF4A | P41235 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907584 | 0.88 | CYP3A4 (0.61) | CYP26A1CYP3A4CYP26B1MAPK1RXRA | |
| SCHEMBL8909052 | 0.85 | CYP3A4 (0.55) | CYP26A1CYP3A4CYP26B1MAPTRARB | |
| SCHEMBL8907526 | 0.81 | CYP3A4 (0.43) | CYP26A1CYP3A4CYP26B1MAPTMAPK1 | |
| SCHEMBL8907772 | 0.77 | PARP15 (0.50) | MAPTRXRAPPARGMAOB | |
| SCHEMBL14371955 | 0.77 | CYP26A1 (0.68) | CYP26A1CYP3A4CYP26B1MAPTMAPK1 | |
| SCHEMBL5419894 | 0.77 | CYP3A4 (0.62) | CYP26A1CYP3A4CYP26B1MAPTMAPK1 | |
| SCHEMBL8907597 | 0.77 | MAOB (0.49) | CYP26A1CYP3A4CYP26B1MAPTMAPK1 | |
| SCHEMBL8839385 | 0.76 | TDP1 (0.50) | CYP3A4MAPTMAPK1RXRAMAOB | |
| SCHEMBL14371956 | 0.76 | CYP3A4 (0.67) | CYP26A1CYP3A4CYP26B1MAPK1RXRA | |
| SCHEMBL5184246 | 0.76 | CYP26A1 (0.74) | CYP26A1CYP3A4CYP26B1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654331-A | SKIN AND RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1997-08-05 | — | — | US | disclosed |
| US-5476860-A | Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD GALDERMA) (FR) | 1995-12-19 | — | — | US | disclosed |