Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194990 | 0.87 | RARG (0.52) | PARP15PPARGRAB9ASMN1; SMN2RXRA | |
| SCHEMBL4943007 | 0.80 | MAOB (0.58) | MEN1KMT2ASMN1; SMN2MAOBHTT | |
| SCHEMBL31336015 | 0.80 | MAOB (0.58) | MEN1KMT2ASMN1; SMN2MAOBHTT | |
| SCHEMBL8907762 | 0.79 | L3MBTL1 (0.49) | MEN1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL9350492 | 0.79 | ALDH1A1 (0.61) | PPARGRXRA | |
| SCHEMBL9263958 | 0.79 | MAOB (0.51) | PPARGMAOBMAPTRXRA | |
| SCHEMBL9261830 | 0.79 | MAOB (0.46) | MEN1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL11280271 | 0.79 | MAOB (0.58) | PARP15MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL3191667 | 0.79 | MAOB (0.58) | PARP15MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL8907967 | 0.77 | CYP26A1 (0.56) | PPARGMAOBMAPTRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654331-A | SKIN AND RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1997-08-05 | — | — | US | disclosed |
| US-5476860-A | Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD GALDERMA) (FR) | 1995-12-19 | — | — | US | disclosed |