Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | ADCY5 | O95622 | 4/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.45 |
| ▸ | AHCY | P23526 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907404 | 0.83 | EGFR (0.49) | ADORA2AADORA1ADCY5FGFR1SLC22A6 | |
| SCHEMBL11222112 | 0.74 | ADORA2A (0.80) | ADORA2AADORA1ADORA2BADCY5 | |
| SCHEMBL29459142 | 0.72 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADCY5ADCY1 | |
| SCHEMBL984944 | 0.72 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADCY5ADCY1 | |
| Hydrochloric Acid SCHEMBL9193028 | 0.71 | ADORA2A (0.97) | ADORA2AADORA1ADORA2BADCY5ADCY1 | |
| SCHEMBL1635576 | 0.70 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADCY5ADCY1 | |
| SCHEMBL16762626 | 0.69 | ADORA2A (0.71) | ADORA2AADORA1ADORA2BADCY5FGFR1 | |
| SCHEMBL1871838 | 0.69 | ADORA2A (0.75) | ADORA2AADORA1ADORA2BAHCY | |
| SCHEMBL19553487 | 0.69 | ADORA2A (0.91) | ADORA2AADORA1ADORA2BADCY5ADCY1 | |
| SCHEMBL67131 | 0.68 | ADORA2A (0.74) | ADORA2AADORA1ADORA2BADCY5ADCY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997034891-A1 | SUBSTITUTED 1,3-THIAZOLIDINES AND 1,3-THIAZOLIDIN-4-ONES, METHOD FOR PREPARING SAME, AND USE THEREOF AS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-09-25 | — | — | WO | claimed |
| WO-1997034891-A1 | SUBSTITUTED 1,3-THIAZOLIDINES AND 1,3-THIAZOLIDIN-4-ONES, METHOD FOR PREPARING SAME, AND USE THEREOF AS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-09-25 | — | — | WO | disclosed |