Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17903350 | 0.87 | PDE4D (0.43) | PDE4DSLC6A2PSEN1PSEN2APH1B | |
| SCHEMBL18542285 | 0.87 | PDE4D (0.43) | PDE4DSLC6A2PSEN1PSEN2APH1B | |
| SCHEMBL7909402 | 0.85 | PDE4D (0.42) | PDE4DSLC6A2PSEN1PSEN2APH1B | |
| SCHEMBL8411521 | 0.81 | PDE4D (0.40) | PDE4DSLC6A2PSEN1PSEN2APH1B | |
| SCHEMBL10904820 | 0.81 | PDE4D (0.55) | PDE4DSLC6A2CYP2C19 | |
| SCHEMBL6451122 | 0.81 | PDE4D (0.55) | PDE4DSLC6A2CYP2C19 | |
| SCHEMBL10904817 | 0.81 | PDE4D (0.55) | PDE4DSLC6A2CYP2C19 | |
| SCHEMBL12573461 | 0.79 | PDE4D (0.53) | PDE4DSLC6A2PSEN1PSEN2APH1B | |
| SCHEMBL17867756 | 0.79 | PDE4D (0.53) | PDE4DSLC6A2BCHEACHE | |
| SCHEMBL17867755 | 0.79 | PDE4D (0.53) | PDE4DSLC6A2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625043-A | ANTITUMOR CHEMOTHERAPY | Priebe, Waldemar | 1997-04-29 | — | — | US | disclosed |