SCHEMBL8908102

SCHEMBL8908102

ClCCCCc1ccccc1[SiH2]Cl

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3482063 0.82 LIPG (0.50) LIPG
SCHEMBL704629 0.80 LIPG (0.43) LIPG
SCHEMBL9715821 0.77 TDP1 (0.42) LIPG
SCHEMBL9715832 0.77 TDP1 (0.42) LIPG
SCHEMBL9715878 0.77 TDP1 (0.42) LIPG
SCHEMBL8075526 0.76 ATM (0.38)
SCHEMBL3481942 0.75 HTR1A (0.36) LIPG
SCHEMBL19215809 0.75 TAAR1 (0.56)
SCHEMBL6679839 0.72 TAAR1 (0.56)
SCHEMBL8522887 0.72 LIPG (0.38) LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5624680-A SKIN ABSORPTION OF DRUGS WITH POLYETHERSILOXANE BLOCK COPOLYMERS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1997-04-29 US disclosed
EP-0710688-A1 HYDROXYSILYL-TERMINATED POLYOXYETHYLENE COMPOUND, QUATERNARY-SALT-TERMINATED BLOCK COPOLYMER, AND PERCUTANEOUS ABSORPTION PROMOTER SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-05-08 EP disclosed