Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | FASN | P49327 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1531846 | 0.91 | MEN1 (0.61) | MEN1KMT2AEPHX2 | |
| SCHEMBL225085 | 0.87 | KMT2A (0.65) | MEN1KMT2AEPHX2 | |
| SCHEMBL217929 | 0.86 | TNK2 (0.43) | MEN1KMT2APTPN1 | |
| SCHEMBL14564207 | 0.84 | TNK2 (0.37) | MEN1KMT2AMGLL | |
| SCHEMBL8908120 | 0.84 | KMT2A (0.43) | MEN1KMT2APTPN1 | |
| SCHEMBL15093765 | 0.82 | MEN1 (0.43) | MEN1KMT2APTPN1 | |
| SCHEMBL15093959 | 0.82 | MEN1 (0.43) | MEN1KMT2APTPN1 | |
| SCHEMBL222919 | 0.82 | MEN1 (0.43) | MEN1KMT2APTPN1 | |
| SCHEMBL11767308 | 0.81 | ELANE (0.52) | MEN1KMT2A | |
| SCHEMBL23962137 | 0.80 | MGLL (0.53) | MEN1KMT2AMGLLPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637254-A | ACRYLATED ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-10 | — | — | US | disclosed |