Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.42 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4223838 | 0.81 | HPGD (0.52) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL13178918 | 0.75 | LMNA (0.55) | APEX1AKR1B1AKR1A1PTGDR2HTT | |
| SCHEMBL8893031 | 0.73 | GRIN2D (0.48) | GPR17APEX1AKR1B1AKR1A1AKR1B10 | |
| SCHEMBL4227686 | 0.72 | MAPK8 (0.49) | ADORA2BMEN1KMT2AHTT | |
| SCHEMBL10487870 | 0.71 | AKR1B1 (0.73) | AKR1B1AKR1A1AKR1B10MEN1KMT2A | |
| SCHEMBL3581111 | 0.69 | APEX1 (0.76) | APEX1MEN1KMT2AHTTLMNA | |
| SCHEMBL29451600 | 0.68 | ADORA2B (0.43) | APEX1AKR1B1GRIN2DGRIN3BGRIA1 | |
| SCHEMBL18180179 | 0.68 | APEX1 (0.62) | APEX1AKR1B1AKR1A1PTGDR2LMNA | |
| SCHEMBL4227625 | 0.67 | MAPT (0.57) | HDAC1HDAC8HDAC6KMT2AHTT | |
| SCHEMBL4216608 | 0.67 | HDAC6 (0.47) | ADORA2BHDAC6KMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997002254-A1 | QUINAZOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-23 | — | — | WO | disclosed |