Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 4/20 | 0.49 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.47 |
| ▸ | TUBB | P07437 | 4/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240622 | 0.87 | KDM4E (0.55) | KDM4ECNR1CNR2KMT2ATOP2A | |
| SCHEMBL4393771 | 0.87 | KDM4E (0.55) | KDM4ECNR1CNR2KMT2ATOP2A | |
| SCHEMBL30306119 | 0.86 | TOP2A (0.55) | KDM4ECNR1CNR2KMT2ATOP2A | |
| SCHEMBL2339241 | 0.86 | TOP2A (0.55) | KDM4ECNR1CNR2KMT2ATOP2A | |
| SCHEMBL5541223 | 0.86 | TOP2A (0.55) | KDM4ECNR1CNR2KMT2ATOP2A | |
| SCHEMBL7848826 | 0.80 | TOP2A (0.39) | KDM4ECNR1CNR2KMT2ATOP2A | |
| SCHEMBL8206695 | 0.79 | STAT3 (0.38) | KDM4ECNR1CNR2KMT2ATOP2A | |
| SCHEMBL8908169 | 0.79 | KDM4E (0.48) | KDM4ECNR1CNR2KMT2AALDH1A1 | |
| SCHEMBL29406062 | 0.79 | KDM4E (0.72) | KDM4ECNR1CNR2KMT2ATOP2A | |
| SCHEMBL2089512 | 0.79 | KDM4E (0.72) | KDM4ECNR1CNR2KMT2ATOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0963977-B1 | Process for the preparation of quinolone- and naphthyridonecarboxylic acids and their esters | BAYER AG (DE) | 2003-05-07 | — | — | EP | disclosed |
| EP-0963977-A1 | Process for the preparation of quinolone- and naphthyridonecarboxylic acids and their esters | Bayer Aktiengesellschaft (DE) | 1999-12-15 | — | — | EP | disclosed |