Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.63 |
| ▸ | DRD3 | P35462 | 6/20 | 0.63 |
| ▸ | DRD4 | P21917 | 5/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106945 | 0.81 | DRD2 (0.83) | DRD2DRD3DRD4 | |
| SCHEMBL8906795 | 0.80 | DRD2 (0.64) | DRD2DRD3DRD4 | |
| SCHEMBL6969948 | 0.78 | DRD2 (1.00) | DRD2DRD3DRD4 | |
| SCHEMBL6976251 | 0.77 | DRD2 (1.00) | DRD2DRD3DRD4 | |
| SCHEMBL8908080 | 0.76 | DRD2 (0.67) | DRD2DRD3DRD4 | |
| SCHEMBL8908194 | 0.75 | DRD2 (1.00) | DRD2DRD3DRD4 | |
| SCHEMBL8907764 | 0.75 | DRD2 (0.57) | DRD2DRD3DRD4 | |
| SCHEMBL6967091 | 0.75 | GRIN1 (0.81) | — | |
| SCHEMBL9825523 | 0.75 | HTR1A (0.54) | DRD2DRD3DRD4 | |
| SCHEMBL6975249 | 0.75 | DRD2 (0.73) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620988-A | Substituted tetrahydropyridines and hydroxypiperidines as central nervous system agents | WARNER-LAMBERT COMPANY (US) | 1997-04-15 | — | — | US | disclosed |
| US-5466698-A | Substituted tetrahydrophyridines and hydroxypiperidines as central nervous system agents | WARNER-LAMBERT COMPANY (US) | 1995-11-14 | — | — | US | disclosed |