⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768822 | 0.73 | — | — | |
| SCHEMBL9194651 | 0.72 | GABRA1 (0.33) | — | |
| SCHEMBL8058780 | 0.72 | — | — | |
| SCHEMBL8846498 | 0.65 | CA1 (0.32) | — | |
| SCHEMBL11824469 | 0.65 | — | — | |
| SCHEMBL479214 | 0.64 | IGF1R (0.32) | — | |
| SCHEMBL60891 | 0.63 | — | — | |
| SCHEMBL6684381 | 0.61 | TAAR1 (0.58) | — | |
| SCHEMBL11332960 | 0.60 | TAAR1 (0.31) | — | |
| SCHEMBL5728945 | 0.60 | L3MBTL1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658975-A | IMPROVED ADHESION, RELEASING PROPERTIES; DRUG DELIVERY | DOW CORNING CORPORATION (US) | 1997-08-19 | — | — | US | disclosed |
| US-5607721-A | Hot-melt silicone pressure sensitive adhesive with siloxylated polyether waxes as additives | DOW CORNING CORPORATION (US) | 1997-03-04 | — | — | US | disclosed |
| US-5482988-A | Hot-melt silicone pressure sensitive adhesive with siloxylated polyether waxes as additives | DOW CORNING CORPORATION (US) | 1996-01-09 | — | — | US | disclosed |
| EP-0663431-A2 | Hot-melt silicone pressure sensitive adhesive with siloxylated polyether waxes as additives | DOW CORNING CORPORATION (US) | 1995-07-19 | — | — | EP | disclosed |
| EP-0663430-A2 | Hot-melt silicone pressure sensitive adhesive with siloxylated allyloxypropane diol copolymers as additives | DOW CORNING CORPORATION (US) | 1995-07-19 | — | — | EP | disclosed |
| US-5371128-A | Blended with a silicone resin and a silicone fluid; viscosity; coating; device for delivering bioactive agent | DOW CORNING CORPORATION (US) | 1994-12-06 | — | — | US | disclosed |