Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31590548 | 0.90 | LMNA (0.53) | POLBLMNACYP2C19MAPTALOX15 | |
| SCHEMBL4026343 | 0.90 | LMNA (0.53) | POLBLMNACYP2C19MAPTALOX15 | |
| SCHEMBL28926278 | 0.87 | POLB (0.50) | POLBLMNACYP2C19MAPTALOX15 | |
| SCHEMBL30346643 | 0.86 | POLB (0.56) | POLBLMNACYP2C19KMT2AKDM4E | |
| SCHEMBL11593694 | 0.86 | POLB (0.56) | POLBLMNACYP2C19KMT2AKDM4E | |
| SCHEMBL29065716 | 0.85 | LMNA (0.52) | LMNACYP2C19MAPTKMT2AKDM4E | |
| SCHEMBL9377084 | 0.85 | POLB (0.54) | POLBCYP2C19KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL8669430 | 0.82 | TSHR (0.55) | POLBLMNAMAPTALOX15KMT2A | |
| SCHEMBL26699195 | 0.82 | KMT2A (0.55) | POLBMAPTALOX15KMT2AKDM4E | |
| SCHEMBL1640485 | 0.81 | KMT2A (0.71) | POLBLMNACYP2C19MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047589-A1 | AMINOPHTHALIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-18 | — | — | WO | claimed |
| JP-4182460-A | — | — | None | — | — | JP | disclosed |
| JP-8012635-A | — | — | None | — | — | JP | disclosed |
| JP-H0812635-A | PRODUCTION OF ACYLAMINOPHTHALIC ACID DERIVATIVE | SUMITOMO CHEM CO LTD | 1996-01-16 | — | — | JP | disclosed |
| JP-H04182460-A | ANILIDE DERIVATIVE AND PREPARATION THEREOF | SUMITOMO CHEM CO LTD | 1992-06-30 | — | — | JP | disclosed |