Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CDC25A | P30304 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6164753 | 0.87 | KDM4E (0.52) | LMNAALDH1A1KDM4ECYP2C19CYP1A2 | |
| SCHEMBL8908317 | 0.85 | POLB (0.50) | LMNAALDH1A1KDM4ECYP2C19TSHR | |
| SCHEMBL9377828 | 0.84 | TSHR (0.56) | LMNAALDH1A1KDM4ECYP2C19CYP1A2 | |
| SCHEMBL7312805 | 0.83 | LMNA (0.71) | LMNAALDH1A1KDM4ECYP2C19CYP1A2 | |
| SCHEMBL11521675 | 0.83 | TSHR (0.68) | LMNAALDH1A1CYP2C19CYP1A2TSHR | |
| SCHEMBL768560 | 0.83 | SMN1; SMN2 (0.52) | LMNAALDH1A1KDM4ECYP2C19CYP1A2 | |
| SCHEMBL15440468 | 0.83 | LMNA (0.49) | LMNAALDH1A1KDM4ECYP2C19CYP1A2 | |
| SCHEMBL16407064 | 0.82 | HSD17B10 (0.61) | LMNAALDH1A1KDM4ECYP2C19CYP1A2 | |
| SCHEMBL1963500 | 0.82 | ATM (0.55) | LMNAALDH1A1KDM4ECYP2C19CYP1A2 | |
| SCHEMBL30346643 | 0.81 | POLB (0.56) | LMNAALDH1A1KDM4ECYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113533539-B | Method for measuring related substances peculiar to Apremix | 江苏先声药业有限公司 | 2023-06-23 | — | — | CN | disclosed |