Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1424324 | 0.86 | ALDH1A1 (0.53) | ALDH1A1LMNACA1CA2CA9 | |
| SCHEMBL8384755 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LMNACA1CA2CA9 | |
| SCHEMBL9544732 | 0.79 | CA12 (0.55) | ALDH1A1LMNACA1CA2CA9 | |
| SCHEMBL8907310 | 0.78 | CA1 (0.46) | ALDH1A1LMNACA1CA2CA9 | |
| SCHEMBL104703 | 0.77 | ALDH1A1 (0.67) | ALDH1A1LMNACA1CA2CA9 | |
| SCHEMBL30945155 | 0.77 | ALDH1A1 (0.67) | ALDH1A1LMNACA1CA2CA9 | |
| SCHEMBL5839700 | 0.76 | ALDH1A1 (0.53) | ALDH1A1LMNACA1CA2CA9 | |
| SCHEMBL20377207 | 0.76 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPK8MAPK9MAPK10 | |
| SCHEMBL1760164 | 0.76 | ALDH1A1 (0.53) | ALDH1A1LMNACA1CA2CA9 | |
| SCHEMBL6120117 | 0.75 | ALDH1A1 (0.51) | ALDH1A1LMNACA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658587-A | TRANSDERMAL PATCH | FLORA INC. (US) | 1997-08-19 | — | — | US | disclosed |
| WO-1997014419-A1 | TRANSDERMAL DELIVERY OF ALPHA ADRENOCEPTOR BLOCKING AGENTS | FLORA INC. (US) | 1997-04-24 | — | — | WO | disclosed |