Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dimethyl Sulfoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Sulfoxide SCHEMBL11133890 | 1.00 | CA1 (0.39) | CA1CA2CA9FFAR3LCK | |
| Dimethyl Sulfoxide SCHEMBL11034597 | 0.88 | — | — | |
| Dimethyl Sulfoxide SCHEMBL28074527 | 0.88 | — | — | |
| Dimethyl Sulfoxide SCHEMBL7058096 | 0.83 | LMNA (0.37) | CA1CA2CA9 | |
| Acetic Acid SCHEMBL4649683 | 0.80 | FFAR3 (0.58) | CA1CA2CA9FFAR3LCK | |
| Acetic Acid SCHEMBL195596 | 0.80 | — | — | |
| Dimethyl Sulfoxide SCHEMBL27555300 | 0.78 | — | — | |
| Dimethyl Sulfoxide SCHEMBL21880072 | 0.78 | — | — | |
| Acetic Acid SCHEMBL10483716 | 0.77 | FFAR3 (0.54) | CA1FFAR3LCKFYN | |
| Dimethyl Sulfoxide SCHEMBL10468517 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693226-A4 | SOLID ELECTROLYTE AND BATTERIES | SHOSHAN HERBERT Z (IL) | 1997-02-26 | — | — | EP | claimed |
| EP-0693226-A1 | SOLID ELECTROLYTE AND BATTERIES | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) | 1996-01-24 | — | — | EP | claimed |
| US-5472808-A | Electronically nonconductive oxide particles, alkali metal salt coating, insulating elastomer, aprotic solvent of low molecular weight polymer | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT, LTD. (IL) | 1995-12-05 | — | — | US | claimed |
| WO-1994024715-A1 | SOLID ELECTROLYTE AND BATTERIES | SHOSHAN, HERBERT, Z. (IL) | 1994-10-27 | — | — | WO | claimed |