Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dimethyl Sulfoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Sulfoxide SCHEMBL29182589 | 0.85 | LMNA (0.35) | LMNAALDH1A1 | |
| Propene SCHEMBL31186377 | 0.85 | — | — | |
| Dimethyl Sulfoxide SCHEMBL8908359 | 0.83 | CA1 (0.39) | CA1CA2CA9 | |
| Dimethyl Sulfoxide SCHEMBL11133890 | 0.83 | CA1 (0.39) | CA1CA2CA9 | |
| Dimethyl Sulfoxide SCHEMBL527169 | 0.83 | — | — | |
| Bicarbonate SCHEMBL226943 | 0.83 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL20954184 | 0.83 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL21612732 | 0.83 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL325796 | 0.83 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL28734227 | 0.83 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0868757-B1 | ELECTROCHEMICAL ENERGY DEVICES USING CONDUCTIVE CERAMIC FIBERS | ADVANCED POWER DEVICES INC (US) | 2004-05-26 | — | — | EP | disclosed |