Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Triacetin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triacetin SCHEMBL15094105 | 0.94 | PRKCA (0.43) | PRKCATDP1ARGAA | |
| Propylene Glycol SCHEMBL20138436 | 0.94 | PRKCA (0.53) | PRKCATDP1 | |
| Triacetin SCHEMBL29242627 | 0.90 | PRKCA (0.47) | PRKCATDP1ARGAA | |
| Isopropyl Alcohol SCHEMBL11286605 | 0.88 | PRKCA (0.54) | PRKCATDP1 | |
| Triacetin SCHEMBL1531419 | 0.88 | PRKCA (0.46) | PRKCATDP1ARGAA | |
| Triacetin SCHEMBL22160048 | 0.88 | PRKCA (0.57) | PRKCATDP1AR | |
| Triacetin SCHEMBL3870 | 0.87 | TDP1 (0.56) | PRKCATDP1ARGAATSHR | |
| Triacetin SCHEMBL821340 | 0.87 | TDP1 (0.56) | PRKCATDP1ARGAATSHR | |
| Triacetin SCHEMBL7194199 | 0.86 | PRKCA (0.45) | PRKCATDP1ARGAA | |
| Triacetin SCHEMBL1698261 | 0.85 | TDP1 (0.50) | PRKCATDP1ARGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2568825-A1 | FLOWABLE LIQUID COMPOSITION | Tristram Pty Ltd. (AU) | 2013-03-20 | — | — | EP | claimed |
| WO-2011140598-A1 | FLOWABLE LIQUID COMPOSITION | TRISCO INVESTMENTS PTY LTD AS TRUSTEE FOR THE TRISCO INVESTMENT TRUST (AU) | 2011-11-17 | — | — | WO | claimed |
| EP-2555761-B1 | THERMALLY STABLE OIL-IN-WATER EMULSIONS CONTAINING AN OIL THAT CONTAINS POLYUNSATURATED FATTY ACIDS | DSM IP ASSETS BV (NL) | 2023-11-15 | — | — | EP | disclosed |
| US-20230346724-A1 | Methods of Making and Using pH Modulating Compositions in the Reproductive System | CRAPAUD BIO INC. (US) | 2023-11-02 | — | — | US | disclosed |
| EP-3863620-A1 | METHODS OF MAKING AND USING PH MODULATING COMPOSITIONS IN THE REPRODUCTIVE SYSTEM | Crapaud Bio, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |
| US-20200129578-A1 | COMPOSITIONS AND METHODS FOR MAINTAINING OR ENHANCING HOMEOSTASIS OR FUNCTION OF FEMALE LOWER REPRODUCTIVE TRACT | BALANCE POINT CAPITAL PARTNERS V, L.P., AS ADMINISTRATIVE AGENT | 2020-04-30 | — | — | US | disclosed |
| US-10357527-B2 | Compositions and methods for maintaining or enhancing homeostasis or function of female lower reproductive tract | FAIRHAVEN HEALTH, LLC (US) | 2019-07-23 | — | — | US | disclosed |
| EP-3442501-A1 | COMPOSITIONS AND METHODS FOR MAINTAINING OR ENHANCING HOMEOSTASIS OR FUNCTION OF FEMALE LOWER REPRODUCTIVE TRACT | Fairhaven Health, LLC (US) | 2019-02-20 | — | — | EP | disclosed |
| US-20180161385-A1 | COMPOSITIONS AND METHODS FOR MAINTAINING OR ENHANCING HOMEOSTASIS OR FUNCTION OF FEMALE LOWER REPRODUCTIVE TRACT | BALANCE POINT CAPITAL PARTNERS V, L.P., AS ADMINISTRATIVE AGENT | 2018-06-14 | — | — | US | disclosed |
| US-9919018-B2 | Compositions and methods for maintaining or enhancing homeostasis or function of female lower reproductive tract | FAIRHAVEN HEALTH, LLC (US) | 2018-03-20 | — | — | US | disclosed |
| US-9913871-B2 | Compositions and methods for maintaining or enhancing homeostasis or function of female lower reproductive tract | FAIRHAVEN HEALTH, LLC (US) | 2018-03-13 | — | — | US | disclosed |
| US-20120083530-A1 | Thermally Stable Oil-in-Water Emulsions Containing an Oil That Contains Polyunsaturated Fatty Acids | MARTEK BIOSCIENCES CORPORATION | 2012-04-05 | — | — | US | disclosed |
| WO-2011127163-A1 | THERMALLY STABLE OIL-IN-WATER EMULSIONS CONTAINING AN OIL THAT CONTAINS POLYUNSATURATED FATTY ACIDS | MARTEK BIOSCIENCES CORPORATION (US) | 2011-10-13 | — | — | WO | disclosed |
| EP-0339811-B1 | AQUEOUS BASED PHARMACEUTICAL COATING COMPOSITION FOR DOSAGE FORMS | ALZA CORPORATION (US) | 1993-02-10 | — | — | EP | disclosed |
| US-5160743-A | Annealed composition for pharmaceutically acceptable drug | ALZA CORPORATION (US) | 1992-11-03 | — | — | US | disclosed |
| US-5024842-A | Annealed coats | ALZA CORPORATION (US) | 1991-06-18 | — | — | US | disclosed |
| US-5006346-A | Delivery system | ALZA CORPORATION (US) | 1991-04-09 | — | — | US | disclosed |
| US-4931285-A | Aqueous based pharmaceutical coating composition for dosage forms | ALZA CORPORATION (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0339811-A2 | Aqueous based pharmaceutical coating composition for dosage forms | ALZA CORPORATION (US) | 1989-11-02 | — | — | EP | disclosed |
| EP-0255485-A2 | Transdermal compositions | WARNER-LAMBERT COMPANY (US) | 1988-02-03 | — | — | EP | disclosed |