Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 14/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8471223 | 0.84 | ALDH1A1 (0.44) | TACR1MEN1KMT2AABCB1 | |
| SCHEMBL8470525 | 0.81 | NPC1 (0.46) | MEN1KMT2A | |
| SCHEMBL8473073 | 0.80 | TACR1 (0.43) | TACR1MEN1KMT2AABCB1 | |
| SCHEMBL27641789 | 0.78 | MEN1 (0.46) | P2RX7TP53MEN1KMT2AABCB1 | |
| SCHEMBL7985622 | 0.77 | GAA (0.50) | TACR1MEN1KMT2AABCB1 | |
| SCHEMBL5410711 | 0.77 | ATM (0.50) | TACR1MEN1KMT2AABCB1 | |
| SCHEMBL31023808 | 0.76 | MGLL (0.55) | MEN1KMT2A | |
| SCHEMBL8473076 | 0.76 | ALDH1A1 (0.43) | MEN1KMT2A | |
| SCHEMBL8473443 | 0.76 | TACR1 (0.76) | TACR1 | |
| SCHEMBL5183732 | 0.76 | MEN1 (0.49) | MEN1KMT2AABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997017338-A1 | SUBSTITUTED 1-INDOLYLPROPYL-4-BENZYLPIPERAZINE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1997-05-15 | — | — | WO | disclosed |