Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.52 |
| ▸ | CTSS | P25774 | 7/20 | 0.48 |
| ▸ | CTSL | P07711 | 6/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10407184 | 0.86 | CTSK (0.46) | CTSKCTSSCTSLCYP1A2CTSB | |
| SCHEMBL9378702 | 0.86 | CTSK (0.46) | CTSKCTSSCTSLCYP1A2CTSB | |
| SCHEMBL11055593 | 0.80 | MEN1 (0.61) | CTSKCTSSCTSLCYP1A2CTSB | |
| SCHEMBL13325457 | 0.77 | KMT2A (0.58) | CTSKCTSSCTSLCYP1A2CTSB | |
| SCHEMBL23604935 | 0.77 | CTSK (0.63) | CTSKCTSSCTSLCYP1A2CTSB | |
| SCHEMBL10612913 | 0.77 | CTSK (0.63) | CTSKCTSSCTSLCYP1A2CTSB | |
| SCHEMBL17235497 | 0.77 | CTSK (0.63) | CTSKCTSSCTSLCYP1A2CTSB | |
| SCHEMBL11515552 | 0.77 | CTSK (0.63) | CTSKCTSSCTSLCYP1A2CTSB | |
| SCHEMBL22753446 | 0.77 | CTSK (0.63) | CTSKCTSSCTSLCYP1A2CTSB | |
| SCHEMBL16215535 | 0.77 | CTSK (0.63) | CTSKCTSSCTSLCYP1A2CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799230-A1 | THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996019482-A1 | THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1996-06-27 | — | — | WO | disclosed |