Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.76 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.76 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.65 |
| ▸ | PGK1 | P00558 | 3/20 | 0.65 |
| ▸ | PGK2 | P07205 | 3/20 | 0.65 |
| ▸ | NT5E | P21589 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908713 | 1.00 | ADORA1 (0.76) | ADORA1ADORA3ADORA2AADORA2BPGK1 | |
| SCHEMBL8908841 | 0.89 | ADORA1 (0.74) | ADORA1ADORA3ADORA2AADORA2BPGK1 | |
| SCHEMBL8908863 | 0.89 | ADORA1 (0.74) | ADORA1ADORA3ADORA2AADORA2BPGK1 | |
| SCHEMBL31201331 | 0.89 | ADORA1 (0.88) | ADORA1ADORA3ADORA2AADORA2BPGK1 | |
| SCHEMBL5396253 | 0.87 | ADORA3 (0.80) | ADORA1ADORA3ADORA2AADORA2BNT5E | |
| SCHEMBL4136507 | 0.87 | ADORA3 (0.80) | ADORA1ADORA3ADORA2AADORA2BNT5E | |
| SCHEMBL7080746 | 0.87 | ADORA3 (0.80) | ADORA1ADORA3ADORA2AADORA2BNT5E | |
| SCHEMBL30581189 | 0.87 | ADORA3 (0.80) | ADORA1ADORA3ADORA2AADORA2BNT5E | |
| SCHEMBL7080749 | 0.87 | ADORA3 (0.80) | ADORA1ADORA3ADORA2AADORA2BNT5E | |
| SCHEMBL8820548 | 0.86 | ADORA1 (0.70) | ADORA1ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603348-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-06-29 | — | — | EP | claimed |
| WO-1993023418-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | claimed |
| US-5672588-A | Purine derivatives | NOVO NORDISK A/S (DK) | 1997-09-30 | — | — | US | disclosed |
| EP-0603348-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993023418-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | disclosed |