Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.71 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.71 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.71 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30307434 | 0.89 | HTR1A (0.61) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL30307406 | 0.89 | HTR1A (0.61) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL13496044 | 0.88 | HTR1A (0.56) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL8907463 | 0.86 | HDAC6 (0.72) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL3051350 | 0.84 | HTR1A (0.69) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL31197362 | 0.84 | HTR1A (0.69) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL15923171 | 0.83 | HTR1A (0.67) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL31197407 | 0.83 | HTR1A (0.67) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL28187442 | 0.82 | HTR1A (0.56) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL8907236 | 0.81 | HDAC6 (0.67) | HTR1AADRA1DADRA1AADRA1BFERMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048705-A1 | POTASSIUM CHANNEL BLOCKERS | UNIVERSITY COLLEGE LONDON (GB) | 1997-12-24 | — | — | WO | disclosed |