Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13411802 | 0.87 | TAAR1 (0.59) | ALDH1A1TAAR1LTA4HPLA2G2ACYP19A1 | |
| SCHEMBL7972707 | 0.85 | ALDH1A1 (0.46) | ALDH1A1TAAR1PLA2G2AAHR | |
| SCHEMBL14812371 | 0.84 | PLA2G2A (0.57) | PLA2G2A | |
| SCHEMBL31447135 | 0.83 | MAPK1 (0.61) | ALDH1A1TAAR1CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL4542738 | 0.83 | MAPK1 (0.61) | ALDH1A1TAAR1CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL182707 | 0.83 | TAAR1 (0.42) | ALDH1A1TAAR1LTA4HPLA2G2AAHR | |
| SCHEMBL321542 | 0.81 | TAAR1 (0.60) | TAAR1LTA4HPLA2G2ASMN1; SMN2 | |
| SCHEMBL10458203 | 0.81 | APP (0.55) | ALDH1A1TAAR1AHRCYP1A1CYP1B1 | |
| SCHEMBL15295203 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TAAR1AHRCYP1A1CYP1B1 | |
| SCHEMBL22498320 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TAAR1AHRCYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |
| US-5661148-A | ANTIHYPOXIC AGENT FOR RESPIRATORY SYSTEM DISORDER | TEIJIN LIMITED (JP) | 1997-08-26 | — | — | US | disclosed |
| US-4289883-A | ADRENERGIC BLOCKING AGENTS OF EXCELLENT CARDIOSELECTIVITY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-15 | — | — | US | disclosed |