Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.45 |
| ▸ | CTSK | P43235 | 6/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 5/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404368 | 1.00 | CTSS (0.45) | CTSSCTSKATMMMP13CTSB | |
| SCHEMBL23691867 | 0.78 | CTSK (0.44) | CTSSCTSKATMMMP13CTSB | |
| SCHEMBL11637926 | 0.78 | KLK5 (0.46) | CTSSCTSKATMMMP13CTSB | |
| SCHEMBL19357527 | 0.78 | CTSK (0.44) | CTSSCTSKATMMMP13CTSB | |
| SCHEMBL4972811 | 0.77 | CTSK (0.43) | CTSSCTSKATMMMP13CTSB | |
| SCHEMBL25076073 | 0.77 | SLC1A3 (0.44) | CTSSCTSKATMMMP13CTSB | |
| SCHEMBL11638332 | 0.74 | SCN9A (0.46) | CTSSCTSKATMMMP13CTSB | |
| SCHEMBL25076071 | 0.74 | KLK5 (0.49) | CTSSCTSKATMMMP13CTSB | |
| SCHEMBL9404277 | 0.74 | CTSS (0.46) | CTSSCTSKATMMMP13CTSB | |
| SCHEMBL8910232 | 0.74 | CTSS (0.46) | CTSSCTSKATMMMP13CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672588-A | Purine derivatives | NOVO NORDISK A/S (DK) | 1997-09-30 | — | — | US | disclosed |