Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | BAX | Q07812 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | PNLIP | P16233 | 1/20 | 0.50 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.48 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12394 | 0.90 | KMT2A (0.54) | LTA4HTSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL6282894 | 0.90 | ALDH1A3 (0.56) | TSHRKMT2AALDH1A1GAAMCL1 | |
| Oxirane SCHEMBL11696690 | 0.90 | LTA4H (0.47) | LTA4HTSHRKMT2AMEN1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL8909178 | 0.87 | KMT2A (0.52) | LTA4HTSHRKMT2AMEN1ALDH1A1 | |
| Phosphine SCHEMBL28772208 | 0.87 | KMT2A (0.52) | LTA4HTSHRKMT2AMEN1ALDH1A1 | |
| Hydrogen Sulfide SCHEMBL27992657 | 0.87 | KMT2A (0.52) | LTA4HTSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL12960634 | 0.86 | KMT2A (0.52) | KMT2AMEN1ALDH1A1LMNATP53 | |
| Hydrochloric Acid SCHEMBL6570767 | 0.85 | KMT2A (0.50) | LTA4HTSHRKMT2AMEN1ALDH1A1 | |
| Methylamine SCHEMBL27820445 | 0.85 | KMT2A (0.50) | KMT2AMEN1ALDH1A1LMNATP53 | |
| Ethylene SCHEMBL28227817 | 0.85 | KMT2A (0.50) | LTA4HTSHRKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354801-A | Synthesis method for pyriproxyfen intermediate | 如东众意化工有限公司 | 2023-06-30 | — | — | CN | claimed |
| EP-3760633-A1 | OXAZINO-QUINAZOLINE AND OXAZINO-QUINAZOLINE TYPE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2021-01-06 | — | — | EP | disclosed |
| US-10005784-B2 | Pyridines, pyrimidines, and pyrazines, as BTK inhibitors and uses thereof | MERCK PATENT GMBH (DE) | 2018-06-26 | — | — | US | disclosed |
| US-10005784-B2 | Pyridines, pyrimidines, and pyrazines, as BTK inhibitors and uses thereof | MERCK PATENT GMBH (DE) | 2018-06-26 | — | — | US | disclosed |
| US-9738648-B2 | Pyridines, pyrimidines, and pyrazines, as BTK inhibitors and uses thereof | MERCK PATENT GMBH (DE) | 2017-08-22 | — | — | US | disclosed |
| US-9738648-B2 | Pyridines, pyrimidines, and pyrazines, as BTK inhibitors and uses thereof | MERCK PATENT GMBH (DE) | 2017-08-22 | — | — | US | disclosed |
| US-20170226113-A1 | PYRIDINES, PYRIMIDINES, AND PYRAZINES, AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-08-10 | — | — | US | disclosed |
| US-20170226113-A1 | PYRIDINES, PYRIMIDINES, AND PYRAZINES, AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-08-10 | — | — | US | disclosed |
| US-20160159804-A1 | PYRIDINES, PYRIMIDINES, AND PYRAZINES, AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2016-06-09 | — | — | US | disclosed |
| US-5110943-A | Herbicides | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1992-05-05 | — | — | US | disclosed |
| US-5037759-A | Oxidation of substituted phenoxy propane by bacteria | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1991-08-06 | — | — | US | disclosed |
| EP-0319100-A2 | Process for the preparation of substituted phenoxy propanoic acids | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170226113-A1 | PYRIDINES, PYRIMIDINES, AND PYRAZINES, AS BTK INHIBITORS AND USES THEREOF | BTK, SYK, LYN | LTA4H 1899/4885TSHR 2251/4885KMT2A 1390/4885 |
| US-20160159804-A1 | PYRIDINES, PYRIMIDINES, AND PYRAZINES, AS BTK INHIBITORS AND USES THEREOF | BTK, SYK, LYN | LTA4H 1899/4885TSHR 2251/4885KMT2A 1390/4885 |
| US-10005784-B2 | Pyridines, pyrimidines, and pyrazines, as BTK inhibitors and uses thereof | BTK, SYK, LYN | LTA4H 2008/4885TSHR 2553/4885KMT2A 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.