Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28606777 | 0.92 | L3MBTL1 (0.58) | PPARGPPARDPPARAL3MBTL1TDP1 | |
| SCHEMBL6779179 | 0.84 | ACHE (0.50) | PPARGPPARDPPARAL3MBTL1TDP1 | |
| SCHEMBL2407551 | 0.83 | PPARG (0.58) | PPARGPPARDPPARAL3MBTL1TDP1 | |
| SCHEMBL13955907 | 0.81 | PPARG (0.55) | PPARGPPARDPPARAL3MBTL1TDP1 | |
| SCHEMBL9836311 | 0.81 | PPARG (0.51) | PPARGPPARDPPARAL3MBTL1TDP1 | |
| SCHEMBL16956547 | 0.81 | PPARG (0.47) | PPARGPPARDPPARAL3MBTL1TDP1 | |
| SCHEMBL9275613 | 0.79 | CYP1A1 (0.43) | PPARGPPARDPPARAL3MBTL1TDP1 | |
| SCHEMBL84033 | 0.79 | PPARG (0.53) | PPARGPPARDPPARAL3MBTL1TDP1 | |
| SCHEMBL27197682 | 0.78 | PPARG (0.53) | PPARGPPARDPPARAL3MBTL1TDP1 | |
| SCHEMBL16953953 | 0.78 | PPARG (0.62) | PPARGPPARDPPARAL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622953-A | DRUG RESISTANT TO ANTICANCER CHEMOTHERAPEUTIC DRUG | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| WO-1994022842-A1 | 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE | BASF AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | disclosed |