Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 8/20 | 0.52 |
| ▸ | RARG | P13631 | 7/20 | 0.52 |
| ▸ | RARA | P10276 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657238 | 0.84 | MEN1 (0.76) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL8911212 | 0.83 | RARB (0.55) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL13856790 | 0.77 | MEN1 (0.65) | MEN1KMT2ATHRBRECQLRARB | |
| SCHEMBL28289972 | 0.76 | KMT2A (0.54) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL7517611 | 0.74 | MEN1 (0.53) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL29462757 | 0.73 | RARG (0.69) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL8766205 | 0.73 | RARG (0.69) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL5833736 | 0.73 | KMT2A (0.50) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL27425286 | 0.72 | MEN1 (0.67) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL7515780 | 0.72 | RARB (0.51) | MEN1KMT2ATHRBRECQLNR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686586-A | Polycyclic aromatic derivatives, process for preparing the same and pharmaceutical and cosmetic compositions containing the same | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1997-11-11 | — | — | US | disclosed |