Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.55 |
| ▸ | RARG | P13631 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | RARA | P10276 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.55 |
| ▸ | GOT1 | P17174 | 1/20 | 0.55 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909360 | 0.83 | MEN1 (0.54) | RARBRARGKMT2ARARAMEN1 | |
| SCHEMBL1082729 | 0.79 | KMT2A (0.61) | RARBRARGKMT2ARARAMEN1 | |
| SCHEMBL3715625 | 0.79 | KMT2A (0.61) | RARBRARGKMT2ARARAMEN1 | |
| Hydrochloric Acid SCHEMBL8460452 | 0.77 | RARB (0.48) | RARBRARGKMT2ARARAMEN1 | |
| SCHEMBL21194961 | 0.76 | GPR35 (0.43) | RARBRARGKMT2ARARAMEN1 | |
| SCHEMBL9300824 | 0.76 | RARB (0.71) | RARBRARGKMT2ARARAMEN1 | |
| SCHEMBL9534725 | 0.75 | KDM4E (0.66) | RARBRARGKMT2ARARAMEN1 | |
| SCHEMBL8459709 | 0.74 | RARB (0.41) | RARBRARGKMT2ARARAMEN1 | |
| SCHEMBL980532 | 0.74 | RARB (0.69) | RARBRARGKMT2ARARAMEN1 | |
| SCHEMBL2770512 | 0.74 | ALDH1A1 (0.67) | TDP1RECQLALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686586-A | Polycyclic aromatic derivatives, process for preparing the same and pharmaceutical and cosmetic compositions containing the same | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1997-11-11 | — | — | US | disclosed |