Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.67 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL680611 | 0.98 | PSIP1 (0.70) | PSIP1HSD11B1MAPTL3MBTL1TDP1 | |
| Fluoride SCHEMBL27365732 | 0.95 | PSIP1 (0.67) | PSIP1HSD11B1MAPTL3MBTL1TDP1 | |
| SCHEMBL21794433 | 0.88 | PSIP1 (0.57) | PSIP1HSD11B1MAPTL3MBTL1TDP1 | |
| SCHEMBL4629307 | 0.85 | CYP2C9 (0.57) | PSIP1CYP2C9CYP2C19CYP1A2GAA | |
| SCHEMBL28365756 | 0.85 | PSIP1 (0.53) | PSIP1HSD11B1MAPTL3MBTL1TDP1 | |
| SCHEMBL777886 | 0.84 | PSIP1 (0.64) | PSIP1HSD11B1MAPTL3MBTL1TDP1 | |
| Ammonia Solution, Strong SCHEMBL6978426 | 0.83 | PSIP1 (0.95) | PSIP1HSD11B1TDP1POLBALDH1A1 | |
| SCHEMBL777601 | 0.83 | PSIP1 (0.67) | PSIP1HSD11B1MAPTL3MBTL1TDP1 | |
| Benzene SCHEMBL6390523 | 0.83 | PSIP1 (0.61) | PSIP1HSD11B1TDP1CYP2C9CYP2C19 | |
| SCHEMBL2445501 | 0.83 | PSIP1 (0.61) | PSIP1HSD11B1TDP1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672588-A | Purine derivatives | NOVO NORDISK A/S (DK) | 1997-09-30 | — | — | US | disclosed |
| EP-0603348-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993023418-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | disclosed |