Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CDC25B | P30305 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | S100A4 | P26447 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | APAF1 | O14727 | 3/20 | 0.48 |
| ▸ | TDP2 | O95551 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 3/20 | 0.48 |
| ▸ | PTPRC | P08575 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14003716 | 0.76 | CDC25B (0.73) | MEN1KMT2ACDC25BRAB9ANPC1 | |
| SCHEMBL7392371 | 0.73 | MAOA (0.38) | MEN1KMT2ACDC25BRAB9ANPC1 | |
| SCHEMBL4552082 | 0.73 | MAOA (0.38) | MEN1KMT2ACDC25BRAB9ANPC1 | |
| SCHEMBL3275841 | 0.71 | CES1 (0.52) | MEN1KMT2ACDC25BRAB9ANPC1 | |
| Anthraquinone SCHEMBL29358690 | 0.69 | MEN1 (1.00) | MEN1KMT2ACDC25BRAB9ANPC1 | |
| Anthraquinone SCHEMBL1901249 | 0.69 | MEN1 (1.00) | MEN1KMT2ACDC25BRAB9ANPC1 | |
| Anthraquinone SCHEMBL14943 | 0.69 | MEN1 (1.00) | MEN1KMT2ACDC25BRAB9ANPC1 | |
| SCHEMBL11580301 | 0.69 | CDC25B (0.61) | MEN1KMT2ACDC25BRAB9ANPC1 | |
| SCHEMBL14031350 | 0.69 | CDC25B (0.61) | MEN1KMT2ACDC25BRAB9ANPC1 | |
| SCHEMBL3498908 | 0.68 | MEN1 (0.52) | MEN1KMT2ACDC25BRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677471-A | Process for the preparation of quinone derivative | EISAI CHEMICAL CO., LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| US-5476955-A | Process for the preparation of a quinone derivative | EISAI CHEMICAL CO., LTD. (JP) | 1995-12-19 | — | — | US | disclosed |
| US-5412124-A | Preparation process of naphthoquinone derivative and intermediate for the preparation thereof | EISAI CHEMICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0613877-A1 | Preparation process of quinone derivative and intermediate for the preparation thereof | EISAI CHEMICAL CO., LTD. (JP) | 1994-09-07 | — | — | EP | disclosed |